A López-Muñiz, I Cuesta Fernandez, E Carbajo, J De Miguel
{"title":"组胺治疗后下丘脑视上核的催产素免疫反应神经细胞。","authors":"A López-Muñiz, I Cuesta Fernandez, E Carbajo, J De Miguel","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Immunohistochemical, morphometric and statistical methods were used to study oxytocin immunoreactive elements in the supraoptic nucleus (SON) of the hypothalamus of 180 male rats. Untreated rats, rats that were given either an intraperitoneal (ip) or intracerebroventricular (icv) injection of histamine (HA) (n = 40 each group) and control animals that received ip or icv injections of saline were included in our study. Oxytocin immunoreactive neurons and oxytocin-labelled nerve tracts were found in the SON of untreated animals. Treatment with saline either intracerebroventricular or intraperitoneally did not modify the oxytocin immunoreaction described for untreated animals. I.c.v. treatment with HA increased the numbers of oxytocin labelled elements. On the contrary, oxytocin immunoreaction after intraperitoneal treatment with HA was similar to that described for control and untreated animals. The morphometric and statistical studies confirmed these findings. The importance and signification of these results are discussed in this paper.</p>","PeriodicalId":75637,"journal":{"name":"Bulletin de l'Association des anatomistes","volume":"78 242","pages":"23-6"},"PeriodicalIF":0.0000,"publicationDate":"1994-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Oxytocin-immunoreactive nerve cells in the supraoptic nucleus of the hypothalamus after treatment with histamine.\",\"authors\":\"A López-Muñiz, I Cuesta Fernandez, E Carbajo, J De Miguel\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Immunohistochemical, morphometric and statistical methods were used to study oxytocin immunoreactive elements in the supraoptic nucleus (SON) of the hypothalamus of 180 male rats. Untreated rats, rats that were given either an intraperitoneal (ip) or intracerebroventricular (icv) injection of histamine (HA) (n = 40 each group) and control animals that received ip or icv injections of saline were included in our study. Oxytocin immunoreactive neurons and oxytocin-labelled nerve tracts were found in the SON of untreated animals. Treatment with saline either intracerebroventricular or intraperitoneally did not modify the oxytocin immunoreaction described for untreated animals. I.c.v. treatment with HA increased the numbers of oxytocin labelled elements. On the contrary, oxytocin immunoreaction after intraperitoneal treatment with HA was similar to that described for control and untreated animals. The morphometric and statistical studies confirmed these findings. The importance and signification of these results are discussed in this paper.</p>\",\"PeriodicalId\":75637,\"journal\":{\"name\":\"Bulletin de l'Association des anatomistes\",\"volume\":\"78 242\",\"pages\":\"23-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1994-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bulletin de l'Association des anatomistes\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin de l'Association des anatomistes","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Oxytocin-immunoreactive nerve cells in the supraoptic nucleus of the hypothalamus after treatment with histamine.
Immunohistochemical, morphometric and statistical methods were used to study oxytocin immunoreactive elements in the supraoptic nucleus (SON) of the hypothalamus of 180 male rats. Untreated rats, rats that were given either an intraperitoneal (ip) or intracerebroventricular (icv) injection of histamine (HA) (n = 40 each group) and control animals that received ip or icv injections of saline were included in our study. Oxytocin immunoreactive neurons and oxytocin-labelled nerve tracts were found in the SON of untreated animals. Treatment with saline either intracerebroventricular or intraperitoneally did not modify the oxytocin immunoreaction described for untreated animals. I.c.v. treatment with HA increased the numbers of oxytocin labelled elements. On the contrary, oxytocin immunoreaction after intraperitoneal treatment with HA was similar to that described for control and untreated animals. The morphometric and statistical studies confirmed these findings. The importance and signification of these results are discussed in this paper.