匈牙利的生态遗传学和药物遗传学研究。

Gene geography : a computerized bulletin on human gene frequencies Pub Date : 1993-12-01

H G Benkmann, L Timar, I Szentesi, U Wimmer, E Lohmann, A Czeizel, H W Goedde

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摘要

对匈牙利12个人群1514个个体进行了α - 1抗胰蛋白酶、血清胆碱酯酶、对氧磷酶和δ -氨基乙酰丙酸脱氢酶多态性、n -乙酰转移酶变异和醛脱氢酶缺乏症的研究。在匈牙利的生态遗传和药物遗传现象的背景下，他们的等位基因频率和环境因素之间可能的关系进行了讨论。

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Ecogenetic and pharmacogenetic studies in Hungary.

12 population groups of Hungary, 1514 individuals altogether, have been studied for polymorphisms of alpha 1antitrypsin, serum cholinesterase, paraoxonase and delta-aminolevulinic acid dehydrase, N-acetyltransferase variation and aldehyde dehydrogenase deficiency. A possible relationship between their allele frequencies and environmental factors in the context of ecogenetic and pharmacogenetic phenomena in Hungary is discussed.

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