{"title":"[亚美尼亚人淋巴肉芽肿病与免疫遗传血液标志物的关联分析]。","authors":"V M Nersisian, N O Musaelian, I G Martirosian","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>A study of 11 immunogenetical blood systems (HLA-A, B C, DR; ABO; Rh-Hr; MNSs; Kidd; Kell-Chellano; Duffy; Lewis; Diego; Gm; Inv) involving 59 antigens was performed in patients of Armenian nationality with lymphogranulomatosis (LGM). Pathogenic associations of HLA, MNSs and Duffy systems with LGM were established. Positive correlations were found (p < 0.001) with HLA phenotypes DR-8, B-14, B-21, SS, Fy(a+b-). These phenotypes have significant correlation with LGM (RR = 4.7-2.1) and can be considered as genetic markers of LGM in the Armenian population.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"40 6","pages":"7-10"},"PeriodicalIF":0.2000,"publicationDate":"1995-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[An analysis of the associational connections of immunogenetic blood markers with lymphogranulomatosis in Armenians].\",\"authors\":\"V M Nersisian, N O Musaelian, I G Martirosian\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A study of 11 immunogenetical blood systems (HLA-A, B C, DR; ABO; Rh-Hr; MNSs; Kidd; Kell-Chellano; Duffy; Lewis; Diego; Gm; Inv) involving 59 antigens was performed in patients of Armenian nationality with lymphogranulomatosis (LGM). Pathogenic associations of HLA, MNSs and Duffy systems with LGM were established. Positive correlations were found (p < 0.001) with HLA phenotypes DR-8, B-14, B-21, SS, Fy(a+b-). These phenotypes have significant correlation with LGM (RR = 4.7-2.1) and can be considered as genetic markers of LGM in the Armenian population.</p>\",\"PeriodicalId\":50427,\"journal\":{\"name\":\"Gematologiya I Transfuziologiya\",\"volume\":\"40 6\",\"pages\":\"7-10\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"1995-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gematologiya I Transfuziologiya\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"HEMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gematologiya I Transfuziologiya","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"HEMATOLOGY","Score":null,"Total":0}
[An analysis of the associational connections of immunogenetic blood markers with lymphogranulomatosis in Armenians].
A study of 11 immunogenetical blood systems (HLA-A, B C, DR; ABO; Rh-Hr; MNSs; Kidd; Kell-Chellano; Duffy; Lewis; Diego; Gm; Inv) involving 59 antigens was performed in patients of Armenian nationality with lymphogranulomatosis (LGM). Pathogenic associations of HLA, MNSs and Duffy systems with LGM were established. Positive correlations were found (p < 0.001) with HLA phenotypes DR-8, B-14, B-21, SS, Fy(a+b-). These phenotypes have significant correlation with LGM (RR = 4.7-2.1) and can be considered as genetic markers of LGM in the Armenian population.
期刊介绍：
The journal publishes original theoretical and clinical studies, lectures, reviews, and practical notes concerning various problems of hematology and clinical and industrial transfusion. The journal provides information on the etiology, pathogenesis, diagnosis and treatment of blood disorders as well as on related non-hematological conditions (internal diseases, poisoning, exposure to ionizing radiation etc.).
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
