肥厚性心肌病猪的超微结构改变

K.-S. Dai , S.-P. Chen , P.-C. Yang , C.-Y. Liu , S.J.T. Mao
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引用次数: 6

摘要

猪自然发生的肥厚性心肌病(HCM)通常以不明原因的心脏肥大和异常的组织学特征为特征(Liu et al., 1994;Dai et al., 1995)。hcm影响心脏的组织学改变具有特征性,可用于诊断该疾病(Dai et al., 1995)。简而言之,这些表现为心肌细胞明显定向障碍,冠状动脉壁增厚伴管腔变窄,心内膜和心肌纤维化。HCM在猪群中的高发病率强烈暗示了遗传基础,因此,台湾养猪研究所已经努力生产一种特殊的HCM猪株。本研究的目的是确定自然发生HCM的猪的超微结构变化。
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Ultrastructural alterations in pigs with naturally occurring hypertrophic cardiomyopathy
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