印度安得拉邦部落红细胞酶的遗传多态性。

Gene geography : a computerized bulletin on human gene frequencies Pub Date : 1995-04-01

J M Naidu, B V Babu, Yasmin, S S Devi

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引用次数: 0

摘要

采用淀粉/聚丙烯酰胺/醋酸纤维素凝胶电泳技术对Konda Dora、Kotia、Bod Mali和Manzai Mali 4个内婚部落群体中一些常见红细胞酶标记的遗传异质性进行了研究。ACP、ESD、PGM1、G6PD、AK1、ADA、6PGD酶和血红蛋白表现出多态性。PGM2、LDH、MDH、SOD、GOT、CA1、CA2、GPI呈单态。在Kotia部落中发现了一个与SOD 2-1杂合子相似的慢变异体，频率为1.31%。本研究的大多数群体对大多数所检测的遗传标记均处于Hardy-Weinberg平衡。结果将根据其他安得拉邦人口的现有数据进行讨论。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Genetic polymorphisms of red cell enzymes in tribes of Andhra Pradesh, India.

The genetic heterogeneity of some common red cell enzyme markers among four endogamous tribal populations namely Konda Dora, Kotia, Bod Mali and Manzai Mali was investigated by starch/polyacrylamide/cellulose acetate gel electrophoresis. ACP, ESD, PGM1, G6PD, AK1, ADA, 6PGD enzymes and haemoglobin exhibited a polymorphism. PGM2, LDH, MDH, SOD, GOT, CA1, CA2 and GPI were monomorphic. A slow variant of SOD similar to that found in SOD 2-1 heterozygote was observed with a frequency of 1.31% among Kotia tribe. Most populations of the present study were in Hardy-Weinberg equilibrium for the majority of the genetic markers examined. The results are discussed in the light of available data on other Andhra populations.

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