英格兰和威尔士的流感监测:1996年10月至1997年6月。

D J Dedman, C A Joseph, M Zambon, D M Fleming, J M Watson
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摘要

本报告概述了1996/ 1997年冬季英格兰和威尔士为监测流感而收集的资料。在英格兰和威尔士,向哨点全科医生咨询“流感和流感样疾病”的人数在11月底开始增加,并在1月初达到顶峰。在英格兰,“聚集性呼吸道疾病”(ARD)的咨询开始增加得稍早,可能是由于呼吸道合胞病毒活动增加的结果,但也在1月初达到高峰。甲型流感(H3N2)病毒在10月初首次发现,但直到11月才发现,活动在1月初达到高峰,与流感样疾病咨询的高峰相吻合。在11月底和12月初发现了少数乙型流感病毒,并在1月中旬记录了大量活动。整个冬季发现的甲型(H3N2)流感病毒和乙型流感病毒数量大致相等,从抗原性上讲,流行的毒株与1996/97年疫苗中包含的毒株相似。虽然就咨询和实验室确诊感染而言,流感活动是“温和的”,但在甲型H3N2流感病毒活动达到高峰的同时,死亡登记也出现了一个高峰。冬季的死亡人数与1989/90年类似,当时英格兰和威尔士发生了最后一次严重的流感流行。
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Influenza surveillance in England and Wales: October 1996 to June 1997.

This report summarises information collected for the surveillance of influenza in England and Wales during the winter of 1996/97. Consultations for 'influenza and influenza-like illness' with sentinel general practitioners in England and Wales began to increase towards the end of November and peaked at the start of January. In England, consultations for 'aggregated respiratory disease' (ARD) began to increase a little earlier, perhaps as a result of increased respiratory syncytial virus activity, but also peaked in early January. Influenza A (H3N2) viruses were first detected in early October, but rarely until November, and activity peaked in early January, coinciding with the peak in consultations for flu-like illness. A few influenza B viruses were detected in late November and early December, and substantial activity was recorded in mid-January. Approximately equal numbers of influenza A(H3N2) and B viruses were identified over the winter as a whole, and circulating strains were antigenically similar to those included in the vaccine for 1996/97. Although influenza activity was 'moderate' in terms of consultations and laboratory confirmed infections, a large peak in death registrations occurred at the same time as influenza A(H3N2) virus activity peaked. The number of deaths during the winter was similar to that seen in 1989/90, when the last severe influenza epidemic occurred in England and Wales.

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