LBP和可溶性CD14在LPS细胞摄取中的作用。

Progress in clinical and biological research Pub Date : 1998-01-01

R I Tapping, J A Gegner, V V Kravchenko, P S Tobias

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引用次数: 0

摘要

LBP和CD14在多种细胞的LPS依赖性激活中的作用已经确立。在这里描述的工作中，我们描述了这些蛋白质在表达膜CD14和不表达膜CD14的细胞结合和摄取LPS中的作用。令人惊讶的是，细胞活化和脂多糖摄取似乎是不同蛋白质需求的独立现象。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Roles for LBP and soluble CD14 in cellular uptake of LPS.

Roles for LBP and CD14 in the LPS dependent activation of a wide variety of cells have been established. In the work described here, we describe roles for these proteins in the binding and uptake of LPS by cells which express membrane CD14 and those which do not. Surprisingly, cell activation and LPS uptake appear to be independent phenomena with different protein requirements.

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