M Timio, P Saronio, S Venanzi, S Gentili, C Verdura, F Timio
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引用次数: 22
摘要
社会心理和文化适应对人口血压趋势的强大影响似乎得到了证实,通过纵向观察,修女在一个隐蔽的秩序。在对144名修女和138名非神职妇女(作为对照组)的培养、体型、血压、饮食和其他变量进行了初步观察后,进行了30年的随访研究。最引人注目的是两组人在血压趋势上的相反趋势。在随访期间,修女们的血压非常稳定。没有人的舒张压升高超过90毫米汞柱。相比之下,对照组女性的血压随着年龄的增长而升高。这导致两组之间收缩压和舒张压的差异逐渐增大(δ >30/15 mm Hg),具有统计学意义。此外,心血管发病率和死亡率(致命性和非致命性事件的结果)在两组中也有所不同。她们在平信徒中比修女中更常见。死亡事件的生存曲线比较有统计学意义(p = 0.0043;P = 0.0056(非致命事件)。总之,将血压和心血管事件的差异归因于心理社会因素的不同负担以及修女保持平静的生活方式似乎是合理的。
Blood pressure in nuns in a secluded order: A 30-year follow-up.
The powerful effect of psychosocial and acculturating influences on population blood pressure trends seems to be confirmed, through longitudinal observations, in the nuns in a secluded order. After initial observations had been made on culture, body form, blood pressure, diet, and other variables in 144 nuns and 138 lay women, included as a control group, a 30-year follow-up study was undertaken. Most striking were opposite trends noted between the two groups in blood pressure trend. During the follow-up period, blood pressure remained remarkably stable among the nuns. None showed an increase in diastolic blood pressure over 90 mm Hg. By contrast, the control women showed the expected increase in blood pressure with age. This resulted in a gradually greater difference (delta>30/15 mm Hg) in systolic and diastolic blood pressure between the two groups, which was statistically significant. In addition, cardiovascular morbidity and mortality, expressed as the outcome of fatal and nonfatal events, were different in the two groups. They were significantly more common in the lay women than in the nuns. Comparisons between survival curves were statistically significant (p = 0.0043 for fatal events; p = 0.0056 for nonfatal events) between the two groups. In conclusion, it seems reasonable to attribute much of the difference in blood pressure and cardiovascular events, to the different burden in psychosocial factor and to the preserved peaceful lifestyle of the nuns.