{"title":"苯的药代动力学模型的结构与验证。","authors":"G C Sinclair, C N Gray, R J Sherwood","doi":"10.1080/00028899908984444","DOIUrl":null,"url":null,"abstract":"<p><p>A pharmacokinetic model for benzene has been developed and validated for the inhalation aspects of its operation. The validation shows reasonable agreement between the model outputs and human biological data for phenol in urine, benzene in alveolar air, and benzene in mixed exhaled air.</p>","PeriodicalId":7930,"journal":{"name":"American Industrial Hygiene Association journal","volume":"60 2","pages":"249-58"},"PeriodicalIF":0.0000,"publicationDate":"1999-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00028899908984444","citationCount":"9","resultStr":"{\"title\":\"Structure and validation of a pharmacokinetic model for benzene.\",\"authors\":\"G C Sinclair, C N Gray, R J Sherwood\",\"doi\":\"10.1080/00028899908984444\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A pharmacokinetic model for benzene has been developed and validated for the inhalation aspects of its operation. The validation shows reasonable agreement between the model outputs and human biological data for phenol in urine, benzene in alveolar air, and benzene in mixed exhaled air.</p>\",\"PeriodicalId\":7930,\"journal\":{\"name\":\"American Industrial Hygiene Association journal\",\"volume\":\"60 2\",\"pages\":\"249-58\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1999-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1080/00028899908984444\",\"citationCount\":\"9\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American Industrial Hygiene Association journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/00028899908984444\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Industrial Hygiene Association journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/00028899908984444","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Structure and validation of a pharmacokinetic model for benzene.
A pharmacokinetic model for benzene has been developed and validated for the inhalation aspects of its operation. The validation shows reasonable agreement between the model outputs and human biological data for phenol in urine, benzene in alveolar air, and benzene in mixed exhaled air.
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