J C Verheijen, S F Bayly, M R Player, P F Torrence, G A van der Marel, J H van Boom
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2-5A-PNA complexes: a novel class of antisense compounds.
This paper presents the fully automated solid phase synthesis of 2-5A-PNA hybrids. These stable antisense probes cause RNase L mediated hydrolysis of target RNA sequences.
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