BTA检查在检测膀胱恶性肿瘤方面优于尿细胞学检查。

Annales chirurgiae et gynaecologiae Pub Date : 1999-01-01

A Heino, S Aaltomaa, M Ala-Opas

{"title":"BTA检查在检测膀胱恶性肿瘤方面优于尿细胞学检查。","authors":"A Heino, S Aaltomaa, M Ala-Opas","doi":"","DOIUrl":null,"url":null,"abstract":"Background and aims: In a prospective study, Bard BTA (bladder tumour antigen) test was compared to voided urine cytology (VUC) in detecting primary and recurrent bladder cancer (BC).Materials and methods: 407 control cystoscopies, BTA test and VUC were performed on 150 patients, of which 96 (23.6%) recurrent tumours were found, and 43 patients with a new BC were noticed.Results: BTA test was superior to VUC in detecting superficial Ta (23% vs. 3%, p < 0.001) and grade 1 (16% vs. 0%, p < 0.001) as well as grade 2 (35% vs. 11%, p < 0.01) tumours. In Tis and T2-T4 tumours as well as in grade 3 tumours both tests performed similarly. The sensitivity of BTA test compared to VUC in detecting recurrent tumours was higher (24 % vs. 9%, p < 0.01), but VUC had more specificity than BTA test (99% vs. 80%, p < 0.001).Conclusions: BTA test was superior to VUC in detecting BC and its recurrence. The simultaneous use of the BTA test and VUC did not add any information in detecting tumour growth in the bladder as compared to the BTA test alone.","PeriodicalId":75495,"journal":{"name":"Annales chirurgiae et gynaecologiae","volume":"88 4","pages":"304-7"},"PeriodicalIF":0.0000,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"BTA test is superior to voided urine cytology in detecting malignant bladder tumours.\",\"authors\":\"A Heino, S Aaltomaa, M Ala-Opas\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background and aims: In a prospective study, Bard BTA (bladder tumour antigen) test was compared to voided urine cytology (VUC) in detecting primary and recurrent bladder cancer (BC).Materials and methods: 407 control cystoscopies, BTA test and VUC were performed on 150 patients, of which 96 (23.6%) recurrent tumours were found, and 43 patients with a new BC were noticed.Results: BTA test was superior to VUC in detecting superficial Ta (23% vs. 3%, p < 0.001) and grade 1 (16% vs. 0%, p < 0.001) as well as grade 2 (35% vs. 11%, p < 0.01) tumours. In Tis and T2-T4 tumours as well as in grade 3 tumours both tests performed similarly. The sensitivity of BTA test compared to VUC in detecting recurrent tumours was higher (24 % vs. 9%, p < 0.01), but VUC had more specificity than BTA test (99% vs. 80%, p < 0.001).Conclusions: BTA test was superior to VUC in detecting BC and its recurrence. The simultaneous use of the BTA test and VUC did not add any information in detecting tumour growth in the bladder as compared to the BTA test alone.\",\"PeriodicalId\":75495,\"journal\":{\"name\":\"Annales chirurgiae et gynaecologiae\",\"volume\":\"88 4\",\"pages\":\"304-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1999-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annales chirurgiae et gynaecologiae\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annales chirurgiae et gynaecologiae","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

背景和目的:在一项前瞻性研究中，将Bard BTA(膀胱肿瘤抗原)检测与空尿细胞学(VUC)检测原发性和复发性膀胱癌(BC)进行比较。材料与方法:对150例患者进行对照膀胱镜检查、BTA检查和VUC检查407例，发现肿瘤复发96例(23.6%)，发现新发BC 43例。结果:BTA检测浅表Ta(23%比3%，p < 0.001)、1级肿瘤(16%比0%，p < 0.001)和2级肿瘤(35%比11%，p < 0.01)优于VUC。在Tis和T2-T4肿瘤以及3级肿瘤中，两种测试结果相似。BTA检测肿瘤复发的敏感性高于VUC(24%比9%，p < 0.01)，但VUC检测肿瘤复发的特异性高于BTA(99%比80%，p < 0.001)。结论:BTA检测检测BC及其复发率优于VUC。与单独使用BTA测试相比，同时使用BTA测试和VUC在检测膀胱肿瘤生长方面没有增加任何信息。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

微信好友朋友圈 QQ好友复制链接

本刊更多论文

BTA test is superior to voided urine cytology in detecting malignant bladder tumours.

Background and aims: In a prospective study, Bard BTA (bladder tumour antigen) test was compared to voided urine cytology (VUC) in detecting primary and recurrent bladder cancer (BC).

Materials and methods: 407 control cystoscopies, BTA test and VUC were performed on 150 patients, of which 96 (23.6%) recurrent tumours were found, and 43 patients with a new BC were noticed.

Results: BTA test was superior to VUC in detecting superficial Ta (23% vs. 3%, p < 0.001) and grade 1 (16% vs. 0%, p < 0.001) as well as grade 2 (35% vs. 11%, p < 0.01) tumours. In Tis and T2-T4 tumours as well as in grade 3 tumours both tests performed similarly. The sensitivity of BTA test compared to VUC in detecting recurrent tumours was higher (24 % vs. 9%, p < 0.01), but VUC had more specificity than BTA test (99% vs. 80%, p < 0.001).

Conclusions: BTA test was superior to VUC in detecting BC and its recurrence. The simultaneous use of the BTA test and VUC did not add any information in detecting tumour growth in the bladder as compared to the BTA test alone.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助