尿毒症中脂蛋白的修饰:氧化、糖基化和氨基甲酰化。

J Galle, C Wanner
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引用次数: 19

摘要

脂蛋白改变发生在尿毒症患者和接受慢性肾脏替代治疗的终末期肾病患者中。脂蛋白修饰的形式包括脂质过氧化、糖基化和氨基酰基化。在这篇简短的综述中,我们讨论了这些形式的脂蛋白修饰及其与各种肾脏疾病的关系。介绍了脂蛋白修饰的分析方法,并介绍了与血管和肾功能相关的功能后果。
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Modification of lipoproteins in uremia: oxidation, glycation and carbamoylation.

Lipoprotein modification occurs in uremic patients and in patients with end stage kidney disease under chronic renal replacement therapy. Forms of lipoprotein modification include lipid peroxidation, glycation, and carbamoylation. In this short review, we discuss the presence of these forms of lipoprotein modification and their association with various renal diseases. Methods to analyze lipoprotein modification are introduced, and functional consequences related to vascular and renal function are presented.

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Author Index Vol. 25, 1999 Manuscript Consultants Contents Vol. 25, 1999 Subject Index Vol. 25, 1999 Subject Index Vol. 25, No. 4–6, 1999
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