重症细菌性腹膜炎的腹部开放治疗及计划再手术。

K Bosscha, P F Hulstaert, M R Visser, T J van Vroonhoven, C van der Werken
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引用次数: 106

摘要

目的:探讨消化道穿孔或吻合口破裂后重症细菌性腹膜炎开腹治疗及计划再手术的效果。设计:回顾性研究。地点:荷兰大学医院。受试者:67例连续患者。干预措施:腹部开放治疗和计划的再手术。主要结局指标:医院发病率和死亡率,长期随访。结果:38例患者出现多器官功能衰竭(MOF), 29例仅需要通气和肌力支持。平均再手术次数为9次。16例出现大出血,16例出现瘘管。住院死亡率为42% (n = 28)。长期发病率,特别是腹壁缺损的数量(n = 10)是相当可观的。结论:重型细菌性腹膜炎虽已开腹治疗并计划再次手术,但病死率仍居高不下,短期和长期发病率均可观。腹部开腹治疗和计划再手术的价值仅在于临床观察,其他常规手术治疗严重细菌性腹膜炎往往失败。
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Open management of the abdomen and planned reoperations in severe bacterial peritonitis.

Objective: To assess the results of open management of the abdomen and planned re-operations in severe bacterial peritonitis after perforation or anastomotic disruption of the digestive tract.

Design: Retrospective study.

Setting: University Hospital, The Netherlands.

Subjects: 67 consecutive patients.

Interventions: Open management of the abdomen and planned reoperations.

Main outcome measures: Hospital morbidity and mortality, long-term follow-up.

Results: 38 patients developed multiple organ failure (MOF), but 29 needed only ventilatory and inotropic support. The mean number of re-operations was nine. 16 patients developed severe bleeding and 16 fistulas. In-hospital mortality was 42% (n = 28). Long-term morbidity, particularly the number of abdominal wall defects (n = 10), was considerable.

Conclusion: Despite open management of the abdomen and planned re-operations, mortality of severe bacterial peritonitis still continues to be too high, and both short and long-term morbidity are appreciable. The value of open management of the abdomen and planned re-operations rests only on the clinical observation that other conventional surgical treatments of severe bacterial peritonitis often fail.

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