腹腔镜与常规回肠结肠切除术治疗克罗恩病的比较。

O Alabaz, A J Iroatulam, A Nessim, E G Weiss, J J Nogueras, S D Wexner
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引用次数: 103

摘要

目的:比较腹腔镜辅助和常规剖腹手术治疗克罗恩病回肠结肠切除术的安全性、疗效和可行性。设计:回顾性研究。环境:私人诊所,美国。对象:1991年8月至1996年7月间行回肠结肠切除吻合术治疗克罗恩病74例,其中常规开腹手术48例,腹腔镜辅助手术26例。主要观察指标:年龄、手术时间、住院时间、早、晚发病、患者主观评价。结果:常规组平均年龄42(+/- 17)岁,腹腔镜辅助组平均年龄40(+/- 15)岁。常规组的平均手术时间为90.5 +/- 3.7分钟,腹腔镜辅助组为150 +/- 1.2分钟(p < 0.0001);常规组的住院时间为9.6 +/- 0.6天,腹腔镜辅助组为7 +/- 0.8天(p < 0.0001)。两组早期并发症的发生率和住院费用没有差异,但在平均随访30个月(范围2-59)时,常规组出现症状性肠梗阻的患者明显更多(15/48比2/26,p = 0.02)。常规组31例(65%),腹腔镜辅助组16例(62%)进行了主观评估。在改变排便习惯、使用排便药物或限制饮食的数量方面,两组之间没有差异,但腹腔镜辅助组患者恢复工作的速度更快(3.7 +/- 1.2周),而常规组患者恢复工作的时间为8.2 +/- 1.1周,美容效果更好(14/16比13/31,p = 0.004),社交和性生活改善的可能性更大(8/16比5/31,p = 0.02)。结论:腹腔镜辅助回肠结肠切除术治疗克罗恩病是安全的,发病率低于常规开腹手术。
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Comparison of laparoscopically assisted and conventional ileocolic resection for Crohn's disease.

Objective: To compare safety, outcome, and feasibility of laparoscopic assisted and conventional laparotomy for ileocolic resection in Crohn's disease.

Design: Retrospective study.

Setting: Private clinic, USA.

Subjects: 74 patients who had ileocolic resection and anastomosis for Crohn's disease between August 1991 and July 1996, 48 through conventional laparotomy and 26 in whom it was laparoscopically assisted.

Main outcome measures: Age, operating time, duration of hospital stay, early and late morbidity, and patients' subjective assessment.

Results: The mean age was 42 (+/- 17) in the conventional group and 40 (+/- 15) in the laparoscopically assisted group. The mean operating time was significantly shorter in the conventional group, 90.5 +/- 3.7 minutes, compared with 150 +/- 1.2 minutes in the laparoscopic-assisted group (p < 0.0001), but they stayed in hospital significantly longer, 9.6 +/- 0.6 days in the conventional group, compared with 7 +/- 0.8 days in the laparoscopic-assisted group (p < 0.0001). There were no differences between the groups in the incidence of early complications or the cost of admission, but at a mean follow up of 30 months (range 2-59) significantly more patients in the conventional group had developed symptomatic bowel obstruction (15/48 compared with 2/26, p = 0.02). 31 patients in the conventional group (65%) and 16 in the laparoscopically assisted group (62%) returned their subjective assessments. There were no differences between the groups in the number with changed bowel habits, use of drugs for bowel movement, or restricted diet, but patients in the laparoscopically assisted group returned to work more quickly (3.7 +/- 1.2 weeks) compared with 8.2 +/- 1.1 weeks in the conventional group, had better cosmetic results (14/16 compared with 13/31, p = 0.004), and were more likely to have improved social and sexual lives (8/16 compared with 5/31, p = 0.02).

Conclusion: Laparoscopically assisted ileocolic resection for Crohn' s disease is safe and has less morbidity than conventional laparotomy.

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