股薄肌转位治疗克罗恩病并发肛周瘘及会阴未愈合伤口。

J Rius, A Nessim, J J Nogueras, S D Wexner
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引用次数: 108

摘要

目的:探讨股薄肌转位法治疗克罗恩病术后慢性复发性瘘及会阴未愈合创面的疗效。设计:回顾性研究。背景:美国学术诊所。研究对象:7例克罗恩病患者,其中3例会阴伤口未愈合并伴有持续性鼻窦;2例曾多次尝试修复直肠阴道瘘;1例直肠尿道瘘;还有一个阴道瘘管。干预:股薄肌转位。主要结局指标:愈合。结果:平均随访18个月(范围3 ~ 30)。所有手术治疗的会阴伤口均在3 ~ 6个月内完全愈合。直肠阴道瘘和直肠尿道瘘患者均在术后1个月愈合。2个瘘管复发,小袋阴道瘘保留,但无症状。结论:股薄肌转位术是治疗克罗恩病术后持续性鼻窦和会阴未愈合创面的可行方法。对于其他类型的克罗恩病相关瘘管或复杂瘘管,其他治疗方法都失败的患者,它也可以作为保护切除术前的一种选择。在得出明确的结论之前,还需要进行更大规模的研究。
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Gracilis transposition in complicated perianal fistula and unhealed perineal wounds in Crohn's disease.

Objective: To assess the efficacy of transposition of gracilis muscle in the treatment of chronic recurrent fistulas and unhealed perineal wounds after proctectomy in patients with Crohn's disease.

Design: Retrospective study.

Setting: Academic clinic, United States.

Subjects: 7 patients with Crohn's disease: 3 had unhealed perineal wounds and persistent sinuses; 2 had had several attempts to repair rectovaginal fistulas; 1 had a rectourethral fistula; and 1 a pouch vaginal fistula.

Intervention: Transposition of the gracilis muscle.

Main outcome measure: Healing.

Results: Mean follow up was 18 months (range 3-30). All patients operated on for unhealed perineal wounds had healed completely within 3-6 months. The patients with a rectovaginal fistula and a rectourethral fistula had both healed by 1 month postoperatively. Two fistulas recurred, and the small pouch-vaginal fistula remained but was asymptomatic.

Conclusions: Transposition of the gracilis is a viable option for the treatment of persistent sinus and unhealed perineal wound after proctectomy for Crohn's disease. It could also be an option before proctectomy for patients with other types of Crohn's-related or complicated fistulas for whom other treatments have failed. A larger series will be required before a definite conclusion can be drawn.

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