外侧内括约肌切开术联合痔疮切除术治疗痔疮:一项随机前瞻性研究。

G Galizia, E Lieto, P Castellano, L Pelosio, V Imperatore, C Pigantelli
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引用次数: 59

摘要

目的:探讨痔患者肛门直肠测压的表现,评价痔切除术加侧内括约肌切开术(LIS)的临床效果和生理后果。设计:随机前瞻性研究。环境:那不勒斯教学医院。患者:连续48例行肛肠测压术的痔疮脱垂患者;10名健康志愿者作为对照。干预措施:记录静息和挤压压力、括约肌长度和直肠抑制反射。6例患者因肛门压力未升高而被排除,共42例患者被随机分组。痔切除术加LIS 22例;20人单独做了痔疮切除术。主要结局指标:发病率、尿失禁和肛肠测压。结果:87.5% (n = 42)的患者发现括约肌异常。单纯痔切除术不影响肛门压力,括约肌切开术后肛门压力恢复正常。患有LIS的患者术后表现优于未患有LIS的患者。4例未行括约肌切开术的患者出现肛门狭窄。没有LIS患者出现大便失禁。结论:高肛压在痔疮患者中很常见,提示其可能具有发病作用;肛门直肠测压法在肛门压力模式的调查中是有用的;当需要时,外侧括约肌切开术可以避免疼痛、尿潴留和狭窄,而且是安全的。
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Lateral internal sphincterotomy together with haemorrhoidectomy for treatment of haemorrhoids: a randomised prospective study.

Objective: To investigate anorectal manometric findings in patients with haemorrhoids and to evaluate the clinical effects and physiological consequences of adding a lateral internal sphincterotomy (LIS) to haemorrhoidectomy.

Design: Randomised prospective study.

Setting: Teaching hospital, Naples.

Patients: 48 consecutive patients with prolapsed piles who had anorectal manometry; 10 healthy volunteers served as controls.

Interventions: Resting and squeeze pressures, sphincter length and rectoanal inhibitory reflex were recorded. 6 patients were excluded because anal pressures were not raised, so 42 patients were randomised. 22 patients had haemorrhoidectomy plus LIS; and 20 had haemorrhoidectomy alone.

Main outcome measures: Morbidity, continence, and anorectal manometry.

Results: Sphincter anomalies were found in 87.5% (n = 42) of patients. Haemorrhoidectomy alone did not affect anal pressures, which returned to the normal ranges after sphincterotomy. Those who had LIS did better postoperatively than those who had did not. 4 patients who did not have a sphincterotomy developed anal strictures. No patient who had LIS developed incontinence of faeces.

Conclusions: High anal pressures are common in patients with haemorrhoids suggesting that they may have a pathogenetic role; anorectal manometry is useful in the investigation of anal pressure patterns; and when indicated, lateral sphincterotomy avoids pain, urinary retention, and stenosis, and is safe.

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