克隆非综合征性听力障碍基因。

British journal of audiology Pub Date : 1999-10-01 DOI:10.3109/03005369909090109

R J Smith, G Van Camp

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引用次数: 1

摘要

超过45个导致常染色体非综合征性听力障碍(NSHI)的基因已经被定位，预计还会有更多的基因存在。为了克隆这些基因，可以使用许多不同的策略。本文重点介绍了四种常用的克隆方法:功能克隆、位置克隆、位置依赖的候选基因克隆和位置独立的候选基因克隆。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cloning genes for non-syndromal hearing impairment.

Over 45 genes that cause autosomal non-syndromic hearing impairment (NSHI) have been localized and many more are predicted to exist. To clone these genes, a number of different strategies can be used. This paper focuses on four general approaches: functional cloning, positional cloning, position-dependent candidate gene cloning, and position-independent candidate gene cloning.

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British journal of audiology

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