柳叶Debregasia salicifolia中的抗菌三萜类化合物。

Erum Akbar, Abdul Malik
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引用次数: 29

摘要

从水杨花赤藓的甲醇部分分离到新的三萜3 β -(反式肉桂酰氧基)-19 α -羟基-醛酸-12-烯(1),与此同时,还首次从该植物中分离到uvaol(2)、3 β、19 α -二羟基-醛酸-12-烯(3)、熊果酸(4)、果酸(5)、果酸甲酯(6)和拷问酸(7)。化合物(1)、(3)和(6)具有显著的抗菌活性。利用广泛的二维核磁共振光谱技术对其结构进行了解析。
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Antimicrobial triterpenes from Debregeasia salicifolia.

New triterpene, 3beta-(trans-cinnamoyloxy)-19alpha-hydroxy-urs-12-ene (1) has been isolated from the methanolic fraction of Debregeasia salicifolia, along with uvaol (2), 3beta,19alpha-dihydroxy-urs-12-ene (3), ursolic acid (4), pomolic acid (5), pomolic acid methyl ester (6) and tormentic acid (7) reported for the first time from this species. The compounds (1), (3) and (6) showed significant antimicrobial activity. The structure elucidation was made with the help of extensive 2D NMR spectroscopic techniques.

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