[从重症监护病房的病人身上分离出的细菌菌株的抗生素类型]。

Revista medica de Panama Pub Date : 1999-01-01
S Vega, M P Atencio, A Quintero, J Sinclair, P Toala
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引用次数: 0

摘要

在重症监护病房中滥用抗生素使得医院环境中多种耐药菌株得以选择。抗生素图显示这些菌株对当前使用的药物的敏感性或耐药性。在本研究中,从内科和外科ICU病房的患者中分离出100株细菌。采用API-20E法对菌株进行鉴定,采用E-test法进行敏感性试验。用WHONET软件进一步分析MIC,该软件可识别抗生素类型。耐药菌株主要为无菌不动杆菌、铜绿假单胞菌和阴沟肠杆菌。共检测出9种抗生素。优势菌株呈现对10种抗生素多重耐药的类型。铜绿假单胞菌有10种抗生素,以CTX、CRO、CTX为主。抗生素类型的确定有助于特定物种的表型鉴定或耐药模式,并有助于对其流行病学分布的跟踪和识别。
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[Antibiotypes of bacterial strains isolated from patients at the intensive care units].

The indiscriminate use of antibiotics in intensive care units has permitted the selection of multiple resistant bacterial strains in the hospital setting. Antibiograms present the sensitivity or resistance of these strains to drugs in current use. In this study, 100 bacterial strains were isolated from patients on medical and surgical ICU wards. The strains were identified by API-20E and sensitivity testing was performed by the E-test procedure. MIC were further analyzed with the WHONET software wich permits the identification of antibiotypes. Acinetobacter anitratus, Pseudomona aeruginosa and Enterobacter cloacae were the most resistant strains. Nine antibiotypes were determinated for A. Anitratus. Predominant strain presented antibiotypes with multiple resistance to ten antibiotics. P. aeruginosa presented 10 antibiotypes, the predominant one being CTX, CRO, CTX. Antibiotype determination allows phenotypic identification or resistance patterns in particular species as well as facilitates follow up and recognition of its epidemiological distribution.

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