Revista medica de Panama最新文献

The racial admixture of a target population can be ascertained by quantifying the contribution to the genetic pool of each of its components (ancestral populations), which could be two, three or more. The racial admixture is of importance for the understanding of results derived from biomedical and anthropological studies. The main objective of this investigation is to determine the population frequencies of genetic systems ABO and Rh and to use these data to calculate the racial admixture of the country and of each sample province, fitting a trihybrid model. To achieve this, the Krieger method, implemented by the computer program Mistura 3, was applied to phenotypic data of systems ABO and Rh in a sample of 4,202 subjects born in seven provinces. In the general population of Panama, 38.72% of genes from the genetic pool have an African origin, 35.87%, an Amerindian origin and 25.40%, a Caucasian origin. In the province of Cocle we found a contribution of 16.47% of African genes, 55.25% of Amerindian genes and 28.28% of Caucasian genes. The province of Colon presents 69.34% of African genes, 25.00% of Amerindian genes and 5.65% of Caucasian genes. In contrast, Chiriquí presents 5.56% of African genes, 50.63% of Amerindian genes and 43.80% of Caucasian genes. The province of Herrera is characterized by the following proportions: 58.45% African genes, 28.44% Amerindian genes and 13.11% Caucasian genes. In the province of Los Santos there is a 62.29% African contribution, a 14.35% Amerindian contribution and a 22.72% Caucasian one. In the province of Panama there is a 57.01%, 26.25% and 16.74% contribution of African, Amerindian and Caucasian genes, respectively. Finally, in Veraguas a contribution of 18.59% of African genes, 44.29% of Amerindian genes and 37.12% of Caucasian genes was found.

We present a trial consisting of 52 kidney transplant patients with stable function, following a transplantation period of 3-6 months (group1), 6-12 months (group2) and more than 12 months (group3) and monitored by CO, C2 and Cyclosporine levels in blood. Mean serum creatinine level were in 1.1, 1.3 and 1.4 Mg/dl for group 1, 2 and 3 respectively. Mean Neoral doses (mg/kg/day) were 5.5, 4.4 and 3.0 for each group respectively. Mean CO (ng/ml) was 347.6 (group 1), 265.6 (group 2) and 207.6 (group 3), and mean C2 was 1353.5, 1098 and 904.2 for each group. 40% (2/5patients) from group2 and 41% (17/41patients) for group 3, had overexposure of the graft to Neoral; meantime 24% (10/41 patients) from group 3 shown C2 levels of underexposure. We conclude CO is a poor predictor of graft exposition to cyclosporine and C2 reflect more exactly this exposure.

The inflammatory pseudotumor of the urinary bladder or pseudosarcomatous fibromyxoid tumor is a benign proliferative mesenchymal spindle cell process, usually polypoid. This rare benign lesion in the majority of the cases have been observed in children and young adults, with only a few cases reported in patients older than 50 years; there are approximately 75 cases in the literature. We present a case of inflammatory pseudotumor verified histologically and treated by tumoral resection and left ureteral reimplantation with antireflux technique. This patient presented initially macroscopic hematuria and required transfusions of packed red cells and frozen fresh plasma. This shows the importance of the diagnosis to establish the definitive treatment as early as possible.

Today angiographic procedures are more frequently used. The need for alternative intravascular contrast agents has increased in order to solve clinical situations like contrast allergy and renal insufficiency. The alternative contrast agent that we have used in thirty patients is CO2 without any complications. CO2 is used solely or in conjunction with Gadolinium or non-ionic contrast media. The alternative contrast agent can be effective, providing sufficient contrast for diagnostic angiography and vascular interventional procedures.

A solid hypoechoic testicular mass must be considered malignant until proved otherwise, even if is nonpalpable. The clinical diagnosis depends upon the appearance of the lesion and the host reaction. A careful history and a thorough physical examination are very important. Complementary studies like the measurement of serum tumor markers, including alpha-fetoprotein and human chorionic gonadotrophin, and scrotal ultrasound help to improve the clinical diagnosis. High-resolution MR imaging with surface coils may provide useful information in selected patients. For some testicular masses, however, the clinical or imaging findings do not fit the typical scenario, so the management is less straightforward. This article reviews the imaging and management of one patient with atypical testicular mass.

Ideal treatment planning in cancer is primarily defined by proper staging. The presence of metastasis in the regional nodal basin must be determined. The best and least invasive manner to achieve this purpose in the nodal basin is by studying the sentinel node. We present the first series of patients treated in Panama with identification and evaluation of the sentinel node. Initially we used only the dye technique and our rate of identification was 77%. When the radioisotope technique was used combined with dye, the localization was successful in 100% of the cases. We recommend the combined technique for a higher yield and minimal false negatives.

We evaluated the biliopancreatic pathology by a non invasive method of Choloangiqgraphy by Magnetc Resonance (the first experience in Panamá). We correlated the method with the retrograde cholangiopancreatography, the surgical findings and the clinical evolution. Our conclusion is that the non invasive method allows us to have confidence in the findings for the biliopancreatic pathology.