Dieter Hassler , Matthias Schnauffer , Hans Ehrfeld , Elke Müller
{"title":"慢性莱姆病成功治疗后特异性免疫反应消失","authors":"Dieter Hassler , Matthias Schnauffer , Hans Ehrfeld , Elke Müller","doi":"10.1016/S1433-1128(04)80031-7","DOIUrl":null,"url":null,"abstract":"<div><p>512 consecutive patients suffering from chronic Lyme borreliosis have been treated according to a standardized therapy regimen which was developed using the results of a controlled trial (<span>Hassler et al., 1990</span>; <span>Hassler, 1992</span>). Follow up was performed for at least 6 (maximum 16) years. In the first two years after initial therapy clinical and serological data were collected every six months including Western blot testing, later once a year.</p></div>","PeriodicalId":100707,"journal":{"name":"International Journal of Medical Microbiology Supplements","volume":"293 ","pages":"Pages 161-164"},"PeriodicalIF":0.0000,"publicationDate":"2004-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1433-1128(04)80031-7","citationCount":"7","resultStr":"{\"title\":\"Disappearance of specific immune response after successful therapy of chronic Lyme borreliosis\",\"authors\":\"Dieter Hassler , Matthias Schnauffer , Hans Ehrfeld , Elke Müller\",\"doi\":\"10.1016/S1433-1128(04)80031-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>512 consecutive patients suffering from chronic Lyme borreliosis have been treated according to a standardized therapy regimen which was developed using the results of a controlled trial (<span>Hassler et al., 1990</span>; <span>Hassler, 1992</span>). Follow up was performed for at least 6 (maximum 16) years. In the first two years after initial therapy clinical and serological data were collected every six months including Western blot testing, later once a year.</p></div>\",\"PeriodicalId\":100707,\"journal\":{\"name\":\"International Journal of Medical Microbiology Supplements\",\"volume\":\"293 \",\"pages\":\"Pages 161-164\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2004-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S1433-1128(04)80031-7\",\"citationCount\":\"7\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Medical Microbiology Supplements\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1433112804800317\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Medical Microbiology Supplements","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1433112804800317","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Disappearance of specific immune response after successful therapy of chronic Lyme borreliosis
512 consecutive patients suffering from chronic Lyme borreliosis have been treated according to a standardized therapy regimen which was developed using the results of a controlled trial (Hassler et al., 1990; Hassler, 1992). Follow up was performed for at least 6 (maximum 16) years. In the first two years after initial therapy clinical and serological data were collected every six months including Western blot testing, later once a year.