[从儿童尸体供体到成人受体的肾移植(综述文章)]。

Sbornik lekarsky Pub Date : 2003-01-01
R Michalský
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引用次数: 0

摘要

所有发达的移植项目的基本问题是可供移植的器官缺乏。在过去的10年里,人们一直在努力使每个移植器官都能发挥几年的功能。这些问题也出现在肾移植项目中。活体供体肾移植在捷克共和国呈上升趋势(2001年超过5%,2002年超过10%),除了实现活体供体肾移植外,唯一的另一种可能是从非理想(次优,边缘)供体处获得肾移植。非理想供体肾移植的短期和长期结果与理想供体肾移植的结果相当。来自非常年轻的儿童尸体供体的肾脏,特别是5岁以下的肾脏是典型的不理想移植。本文介绍了捷克共和国在从尸体供体获取器官以及肾脏移植方面的国际地位。它简短地总结了肾脏移植的历史,同时它处理实现肾移植从儿童尸体供体到成人受体。从儿童尸体捐赠者肾移植的新划分分为四组,根据他们的年龄介绍。本文对目前的手术技术进行了描述,并讨论了一些术后并发症的问题,特别是原发性移植物无功能的发生率较高。强调三岁以下供者的肾脏应作为一个块移植给单个受者的原则。综上所述,笔者根据自己的经验,建议这些移植的实现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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[Kidney transplantation from paediatric cadaveric donors to adult recipients (review article)].

The basic problem of all developed transplant programs is organs deficiency available for transplantation. There is an effort within last 10 years to get each organ for transplantation that it is supposed to be functional for several years. These problems also occur in the program of kidney transplantation. Apart from realizing of kidney transplantations from donors alive, which have an increasing tendency in Czech Republic (in 2001 more than 5%, in 2002 more than 10%), there is the only another possibility to get kidney grafts from non-ideal (suboptimal, marginal) donors. Both short-term and long-term results of kidney transplantation from non-ideal donors are comparable with the transplantation results from ideal donors. The kidneys from very young paediatric cadaveric donors, especially up to five years are the typical example of non-ideal graft. The article introduces the international position of the Czech Republic in organ procurement from cadaveric donors as well as in kidney transplantations. It shortly summarizes the history of kidney transplantations and at the same time it deals with realizing of kidney transplantation from paediatric cadaveric donors to adult recipients. The new division of kidney grafts from paediatric cadaveric donors into four groups according to their age is introduced. All at once the present surgical technique is described and the problems of some post-operative complications are discussed, especially the higher occurrence of primary graft non-function. The principle that kidneys from donor up to three years should be transplanted as a block to the single recipient is emphasized. In conclusion the author recommends, on the basis of his own experiences, the realizing of these transplantations.

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