1987-1995年瑞典腹腔镜和开腹胆囊切除术后的再干预:来自医院出院记录的数据分析

Axel Ros, Bengt Haglund, Erik Nilsson
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引用次数: 12

摘要

目的:了解1987 ~ 1995年瑞典胆囊切除术及胆囊切除术后再干预的发生率,比较单纯腹腔镜胆囊切除术与常规开腹胆囊切除术(不探查胆总管或同时手术)的死亡率和再干预率。设计:分析来自瑞典国家登记册的数据。地点:瑞典,两家医院和政府部门。主要观察指标:胆囊切除术后1年内再入院时的死亡率和再干预情况,分类为胆管再手术、内镜或经皮再干预、伤口并发症、出血或不明原因再手术。结果:1987-89和1993-95年间,胆囊切除术的发生率男性从0.97例上升到1.04例,女性从1.70例上升到2.05例。胆管再手术从1987年到1991年下降,但此后恢复到以前的水平。从1987年到1995年,内镜下再介入手术增加了10倍,而一般并发症和死亡率没有明显变化。在单纯胆囊切除术中,腹腔镜手术与内镜再干预风险增加相关,优势比为1.8 (95% CI为1.2 ~ 2.6),与术后死亡风险较低相关,优势比为0.5 (95% CI为0.3 ~ 0.8)。结论:发病率、死亡率和再入院是胆囊手术的重要终点。引入腹腔镜胆囊切除术后,这些变量发生了显著变化。
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Reintervention after laparoscopic and open cholecystectomy in Sweden 1987-1995: analysis of data from a hospital discharge register.

Objective: To find out the incidence of cholecystectomy and of reintervention after cholecystectomy in Sweden 1987 to 1995, and to compare mortality and reintervention after simple laparoscopic and conventional open cholecystectomy (without exploration of the common bile duct or simultaneous operation).

Design: Analysis of data from Swedish national registers.

Setting: Two hospitals and government department, Sweden.

Main outcome measures: Mortality and reintervention during readmission within one year after cholecystectomy classified as: reoperation on bile duct, endoscopic or percutaneous reintervention, or reoperation for wound complication, bleeding, or unspecified cause.

Results: Incidence of cholecystectomy rose between 1987-89 and 1993-95 from 0.97 to 1.04 for men and from 1.70 to 2.05 operations/1000 inhabitants for women. Reoperation on the bile ducts declined from 1987 to 1991 but returned to previous levels thereafter. Endoscopic reinterventions increased tenfold from 1987 to 1995, whereas those for general complications and mortality did not change significantly. Among simple cholecystectomies laparoscopic surgery was associated with an increased risk of endoscopic reintervention, odds ratio 1.8 (95% CI 1.2 to 2.6), and with a lower risk for postoperative mortality, odds ratio 0.5 (95% CI 0.3 to 0.8).

Conclusions: Incidence, mortality, and readmission with reintervention are important endpoints in gallbladder surgery. Significant changes in these variables were identified after the introduction of laparoscopic cholecystectomy.

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