{"title":"[胃饥饿素在调节能量稳态中的作用]。","authors":"Ewa Otto Buczkowska","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Ghrelin, a novel 28 amino acid peptide, is the endogenous ligand for the growth hormone secretagogue receptor. The stomach is the primary source of circulating ghrelin, but it is also produced by the intestines, kidneys, hypothalamus, pituitary, placenta and pancreas. Ghrelin has been recognized as an important regulator of GH secretion and have important roles in energy homeostasis, glucose and lipid metabolism, reproduction, cardiovascular function, and immunity. Ghrelin has been shown to have a physiological role in the control of food intake, acting as an orexigenic hormone, probably by stimulating NPY production in contrast to the actions of leptin.</p>","PeriodicalId":11550,"journal":{"name":"Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych","volume":"11 1","pages":"39-42"},"PeriodicalIF":0.0000,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The role of ghrelin in the regulation of energy homeostasis].\",\"authors\":\"Ewa Otto Buczkowska\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Ghrelin, a novel 28 amino acid peptide, is the endogenous ligand for the growth hormone secretagogue receptor. The stomach is the primary source of circulating ghrelin, but it is also produced by the intestines, kidneys, hypothalamus, pituitary, placenta and pancreas. Ghrelin has been recognized as an important regulator of GH secretion and have important roles in energy homeostasis, glucose and lipid metabolism, reproduction, cardiovascular function, and immunity. Ghrelin has been shown to have a physiological role in the control of food intake, acting as an orexigenic hormone, probably by stimulating NPY production in contrast to the actions of leptin.</p>\",\"PeriodicalId\":11550,\"journal\":{\"name\":\"Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych\",\"volume\":\"11 1\",\"pages\":\"39-42\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2005-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[The role of ghrelin in the regulation of energy homeostasis].
Ghrelin, a novel 28 amino acid peptide, is the endogenous ligand for the growth hormone secretagogue receptor. The stomach is the primary source of circulating ghrelin, but it is also produced by the intestines, kidneys, hypothalamus, pituitary, placenta and pancreas. Ghrelin has been recognized as an important regulator of GH secretion and have important roles in energy homeostasis, glucose and lipid metabolism, reproduction, cardiovascular function, and immunity. Ghrelin has been shown to have a physiological role in the control of food intake, acting as an orexigenic hormone, probably by stimulating NPY production in contrast to the actions of leptin.
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