对抑郁症作为心脏危险因素的思考。

IF 2.9 3区 医学 Q2 PSYCHIATRY Psychosomatic Medicine Pub Date : 2005-05-01 DOI:10.1097/01.psy.0000162253.07959.db
Nancy Frasure-Smith, François Lespérance
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引用次数: 296

摘要

目的:北美主要心脏病组织目前并未将抑郁症列为官方认可的心脏病危险因素,但许多行为医学专家认为抑郁症是一个重要的风险因素。我们想知道现有的数据中缺少了什么。方法:使用Medline、Current Contents和PsychInfo数据库对将抑郁和抑郁症状与心脏病结局联系起来的文献进行系统回顾。由于以前的审查,我们特别关注2001年至2003年的出版物。结果:我们确定了21篇病因学和43篇预后出版物,这些出版物具有前瞻性设计,使用公认的抑郁症测量方法,并包括客观结果测量方法。我们还发现了79篇综述文章。除了样本量、样本特征和测量时间的问题外,我们还注意到抑郁症定义的异质性、来自相同数据集的频繁重复出版物、结果测量的异质性、协变量选择方法的多样性以及综述文章的优势,所有这些因素都无法帮助说服怀疑论者。结论:尽管存在这些问题,来自具有公认的抑郁指标和客观结果测量的前瞻性研究的大部分数据支持抑郁是心脏危险因素。
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Reflections on depression as a cardiac risk factor.

Objective: Major North American cardiology organizations do not currently list depression among the officially recognized cardiac risk factors, yet many behavioral medicine specialists believe depression to be an important risk. We wondered what was missing from the available data.

Methods: The Medline, Current Contents, and PsychInfo databases were used to perform a systematic review of the literature linking depression and depressive symptoms with cardiac disease outcomes. Because of previous reviews, we paid particular attention to publications from 2001 to 2003.

Results: We identified 21 etiologic and 43 prognostic publications that had prospective designs, used recognized measures of depression, and included objective outcome measures. We also identified 79 review articles. In addition to issues of sample size, sample characteristics, and timing of measures, we noted heterogeneity in the definitions of depression, frequent repeat publications from the same data sets, heterogeneity of outcome measures, a variety of approaches for covariate selection, and a preponderance of review articles, all factors that cannot help to convince skeptics.

Conclusions: Despite these issues, the bulk of the data from prospective studies with recognized indices of depression and objective outcome measures is supportive of depression as a cardiac risk factor.

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来源期刊
Psychosomatic Medicine
Psychosomatic Medicine 医学-精神病学
CiteScore
5.10
自引率
0.00%
发文量
258
审稿时长
4-8 weeks
期刊介绍: Psychosomatic Medicine is the official peer-reviewed journal of the American Psychosomatic Society. The journal publishes experimental, clinical, and epidemiological studies on the role of psychological and social factors in the biological and behavioral processes relevant to health and disease. Psychosomatic Medicine is an interdisciplinary peer-reviewed journal devoted to high-quality science on biobehavioral mechanisms, brain-behavior interactions relevant to physical and mental disorders, as well as interventions in clinical and public health settings. Psychosomatic Medicine was founded in 1939 and publishes interdisciplinary research articles relevant to medicine, psychiatry, psychology, and other health-related disciplines. The print journal is published nine times a year; most articles are published online ahead of print. Supplementary issues may contain reports of conferences at which original research was presented in areas relevant to the psychosomatic and behavioral medicine.
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