{"title":"大鼠神经系统F3/contactin mRNA非翻译区多态性","authors":"Claire Rome , Valérie Roullot, Franck Couillaud","doi":"10.1016/j.molbrainres.2005.05.012","DOIUrl":null,"url":null,"abstract":"<div><p><span><span><span>F3/contactin is a neural adhesion molecule implicated in various physiological processes. In </span>rat brain tissues, we cloned various mRNA with the same coding region but differing in 3′ and 5′UTR. The 3′UTR presents two </span>polyadenylation<span> signals. At the 5′ end, we identified two leader exons, multiple transcription initiation sites and splicing events, leading to at least 19 different 5′UTR. The </span></span><em>F3</em>/<em>contactin</em> rat gene differs from the mouse gene for two reasons: (1) it contains two additional untranslated exons that are alternatively spliced and (2) it lacks the homologue mouse untranslated exon 0.</p></div>","PeriodicalId":100932,"journal":{"name":"Molecular Brain Research","volume":"139 1","pages":"Pages 184-191"},"PeriodicalIF":0.0000,"publicationDate":"2005-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.molbrainres.2005.05.012","citationCount":"3","resultStr":"{\"title\":\"Polymorphism of the untranslated regions of the F3/contactin mRNA in the rat nervous system\",\"authors\":\"Claire Rome , Valérie Roullot, Franck Couillaud\",\"doi\":\"10.1016/j.molbrainres.2005.05.012\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span><span><span>F3/contactin is a neural adhesion molecule implicated in various physiological processes. In </span>rat brain tissues, we cloned various mRNA with the same coding region but differing in 3′ and 5′UTR. The 3′UTR presents two </span>polyadenylation<span> signals. At the 5′ end, we identified two leader exons, multiple transcription initiation sites and splicing events, leading to at least 19 different 5′UTR. The </span></span><em>F3</em>/<em>contactin</em> rat gene differs from the mouse gene for two reasons: (1) it contains two additional untranslated exons that are alternatively spliced and (2) it lacks the homologue mouse untranslated exon 0.</p></div>\",\"PeriodicalId\":100932,\"journal\":{\"name\":\"Molecular Brain Research\",\"volume\":\"139 1\",\"pages\":\"Pages 184-191\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2005-09-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.molbrainres.2005.05.012\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Molecular Brain Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0169328X05002391\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular Brain Research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0169328X05002391","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Polymorphism of the untranslated regions of the F3/contactin mRNA in the rat nervous system
F3/contactin is a neural adhesion molecule implicated in various physiological processes. In rat brain tissues, we cloned various mRNA with the same coding region but differing in 3′ and 5′UTR. The 3′UTR presents two polyadenylation signals. At the 5′ end, we identified two leader exons, multiple transcription initiation sites and splicing events, leading to at least 19 different 5′UTR. The F3/contactin rat gene differs from the mouse gene for two reasons: (1) it contains two additional untranslated exons that are alternatively spliced and (2) it lacks the homologue mouse untranslated exon 0.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
