SIAscopy——一种新的非侵入性黑色素瘤诊断技术。

Małgorzata Michalska, Grazyna Chodorowska, Dorota Krasowska
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摘要

分光光度法皮内分析(SIA)是一种快速、无创、完全安全的色素性皮肤病变鉴别方法,与临床和皮肤镜诊断黑色素瘤相比具有明显的优势。它很容易执行,并允许检查皮肤病变具有很高的准确性和高度客观的方式。该方法的灵敏度达到96%。研究还表明,SIAscopy是最可靠和可重复的黑色素瘤非侵入性诊断技术。这种被称为SIAscope的设备首先向皮肤发射400到950纳米的无害辐射,然后测量每个波长的反射光量。这是可能的,因为皮肤的各个组成部分的光学特性各不相同。它们吸收和/或反射不同程度的光,并优先与特定波长的光相互作用。从光谱测量中,SIAscope提取有关皮肤层内黑色素、胶原蛋白和血红蛋白(即血管)的位置、数量和分布的信息。然后,数据作为siagraps显示在屏幕上,siagraps是数字信息的图形表示。已经确定黑色素瘤显示一种特征性的siasscopy图像。它可以让医生在没有太多经验的情况下及早诊断出肿瘤。
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SIAscopy--a new non-invasive technique of melanoma diagnosis.

Spectrophotometric Intracutaneous Analysis (SIA) is a fast, non-invasive and completely safe method of pigmented skin lesions differentiation with distinct advantages over clinical and dermatoscopic diagnosis of melanoma. It is easy to perform and allows to examine the skin lesions with great accuracy and in a highly objective manner. The sensitivity of the method reaches the value of 96%. It has also been shown that SIAscopy is the most reliable and reproducible of melanoma non-invasive diagnostic techniques. The device, termed SIAscope operates by emission of harmless radiation ranging from 400 to 950 nm into the skin and next, by a measurement of the reflected light quantity for each wavelengths. It is possible because individual components of the skin vary in their optical properties. They absorb and/or reflect light to a various degree and interact preferentially with particular wavelengths of light. From the spectral measurements SIAscope extracts information regarding location, quantity and distribution of melanin, collagen and haemoglobin (i.e. vascularity) within the layers of the skin. The data are then displayed on the screen as the SIAgraphs, which are graphical representations of digital information. It has been established that melanoma displays a characteristic SIAscopic image. It allows doctors to diagnose the tumor early enough even without much experience.

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