线粒体钙化。

Immunometabolism Pub Date : 2021-01-01 Epub Date: 2021-01-29 DOI:10.20900/immunometab20210008
Bhargavi Duvvuri, Christian Lood
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引用次数: 11

摘要

线粒体最吸引人的一个方面是它们在磷酸盐存在的情况下积累和储存大量钙的非凡能力,导致线粒体钙化。在本文中,我们简要介绍了调节线粒体钙稳态的机制,然后对导致线粒体钙化的线粒体内磷酸钙颗粒的形成和表征及其与身体组织生理和病理钙化的相关性进行了广泛的综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Mitochondrial Calcification.

One of the most fascinating aspects of mitochondria is their remarkable ability to accumulate and store large amounts of calcium in the presence of phosphate leading to mitochondrial calcification. In this paper, we briefly address the mechanisms that regulate mitochondrial calcium homeostasis followed by the extensive review on the formation and characterization of intramitochondrial calcium phosphate granules leading to mitochondrial calcification and its relevance to physiological and pathological calcifications of body tissues.

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