沙特阿拉伯多发性硬化症患者计划生育:专家共识。

IF 2.2 Q3 CLINICAL NEUROLOGY Multiple Sclerosis International Pub Date : 2021-02-15 eCollection Date: 2021-01-01 DOI:10.1155/2021/6667006
Mohammed Al Jumah, Yaser Al Malik, Nuha M AlKhawajah, Jameelah Saeedi, Ibtisam AlThubaiti, Saeed Bohlega, Reem F Bunyan, Edward J Cupler, Ahmed ElBoghdady, Ahmed Hassan, Eman Nassim Ali, Marinella Clerico
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引用次数: 5

摘要

在沙特阿拉伯王国(KSA),超过一半的多发性硬化症(MS)患者是育龄妇女。在我们这个地区,养家是妇女重要的人生目标。然而,对复发缓解型多发性硬化症(RRMS)的临床病程以及疾病缓解药物(dmd)对胎儿的影响的恐惧和误解,导致许多妇女降低了抚养家庭的期望,有时甚至达到完全避免怀孕的程度。可用于管理RRMS的dmd数量的增加,以及最近关于其在怀孕期间影响的研究,扩大了这些妇女的管理选择。干扰素β现在在欧洲有妊娠期间使用的指征(根据临床需要),并可在母乳喂养期间使用。对于已经或即将怀孕的RRMS疾病活动度较低的女性,醋酸格拉替默是另一种可能的选择;Natalizumab可用于疾病活动度较高的患者长达30周。在可能的情况下,医生需要支持和鼓励妇女追求充实的家庭生活的梦想,必要时通过对RRMS的积极干预来支持,这些干预越来越多地基于证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Family Planning for People with Multiple Sclerosis in Saudi Arabia: an Expert Consensus.

More than half of all patients with multiple sclerosis (MS) in the Kingdom of Saudi Arabia (KSA) are women of childbearing age. Raising a family is an important life goal for women in our region of the world. However, fears and misconceptions about the clinical course of relapsing-remitting MS (RRMS) and the effects of disease-modifying drugs (DMDs) on the foetus have led many women to reduce their expectations of raising a family, sometimes even to the point of avoiding pregnancy altogether. The increase in the number of DMDs available to manage RRMS and recent studies on their effects in pregnancy have broadened management options for these women. Interferon beta now has an indication in Europe for use during pregnancy (according to clinical need) and can be used during breastfeeding. Glatiramer acetate is a further possible option for women with lower levels of RRMS disease activity who are, or about to become, pregnant; natalizumab may be used up to 30 weeks in patients with higher levels of disease activity. Where possible, physicians need to support and encourage women to pursue their dream of a fulfilling family life, supported where necessary by active interventions for RRMS that are increasingly evidence based.

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来源期刊
Multiple Sclerosis International
Multiple Sclerosis International CLINICAL NEUROLOGY-
自引率
0.00%
发文量
6
审稿时长
15 weeks
期刊介绍: Multiple Sclerosis International is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to all aspects of multiple sclerosis, including clinical neurology, neuroimaging, neuropathology, therapeutics, genetics, neuroimmunology, biomarkers, psychology and neurorehabilitation.
期刊最新文献
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