双侧阳极经颅直流电刺激与跑步机训练对脑瘫儿童脑活动、步态功能、参与水平和享受的影响:一项随机对照试验方案。

IF 1.1 4区 医学 Q4 CLINICAL NEUROLOGY Developmental Neurorehabilitation Pub Date : 2022-02-01 Epub Date: 2021-03-27 DOI:10.1080/17518423.2021.1905730
Hikmat Hadoush, Nihad A Almasri, Nasim Alnuman
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引用次数: 2

摘要

背景:脑瘫(CP)具有双侧感觉-运动皮层兴奋性改变。在过去的研究中,研究人员应用单侧阳极经颅直接刺激(tDCS),结果不一致。目的:探讨跑步机训练与单侧或双侧淋巴结tDCS刺激对cp患儿脑活动、步态和身体功能的影响。设计:随机临床试验。参与者:80名CP患儿将被分为:跑步机组/双侧tdcs组、跑步机组/单侧tdcs组、跑步机组/假tdcs组和跑步机组。另外20名神经正常的儿童将被招募进行比较。干预:计划干预将实施10次跑步机训练(最高地面速度的50%),单侧tdcs在左侧感觉-运动区域,或双侧tdcs在左右感觉-运动区域。脑活动、步态、身体功能和参与将在干预前、干预后和一个月的随访中进行评估。结果和讨论:本研究将有助于现有的关于在CP儿童中使用tDCS刺激的发现,并有助于我们对计划结果测量的适当性的理解。
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The Effect of Bilateral Anodal Transcranial Direct Current Stimulation versus Treadmill Training on Brain Activities, Gait Functions, Level of Participation and Enjoyment of Children with Cerebral Palsy: A Randomized Controlled Trial Protocol.

Background: Cerebral palsy (CP) possesses bilateral sensory-motor cortical excitability alterations. In past studies, researchers have applied unilateral anodal transcranial direct stimulation (tDCS) with inconsistent findings.

Objective: Examining the effects of treadmill training with either unilateral or bilateral anodal tDCS stimulation on brain activities, gait, and body functions of children with CP.

Design: Randomized-clinical-trial.

Participants: Eighty children with CP will be allocated into: treadmill/bilateral-tDCS, treadmill/unilateral-tDCS, treadmill/sham-tDCS, and treadmill groups. Additional 20 neurotypical children will be recruited for comparison.

Intervention: Planned intervention will implement ten-sessions of treadmill training (50% of maximum-ground speed) either with unilateral-tDCS over left sensory-motor, or bilateral-tDCS over left/right sensory-motor areas. Brain activities, gait, body functions, and participation will be assessed at pre-intervention, post-intervention, and at one-month follow-up.

Result and discussion: This study would contribute to extant findings on the use of tDCS stimulation in children with CP and to our understanding of the appropriateness of the planned outcome measures.

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来源期刊
Developmental Neurorehabilitation
Developmental Neurorehabilitation CLINICAL NEUROLOGY-PEDIATRICS
CiteScore
3.10
自引率
0.00%
发文量
27
审稿时长
6-12 weeks
期刊介绍: Developmental Neurorehabilitation aims to enhance recovery, rehabilitation and education of people with brain injury, neurological disorders, and other developmental, physical and intellectual disabilities. Although there is an emphasis on childhood, developmental disability can be considered from a lifespan perspective. This perspective acknowledges that development occurs throughout a person’s life and thus a range of impairments or diseases can cause a disability that can affect development at any stage of life.
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