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引用次数: 17

摘要

成像传统上分为两个不同的学科:功能成像和结构成像。功能成像包括核医学(单光子发射计算机断层扫描[SPECT]和正电子发射断层扫描[PET])、放射自显影、磁共振波谱(MRS)和脑磁成像(MEG)等应用,而结构或解剖成像包括平面放射成像、x射线计算机断层扫描(CT)和磁共振成像(MRI)。然而,今天,由于软件融合的进步和多模态(SPECT/CT, PET/CT)扫描仪的发展,这些之间的区别正在变得模糊。利用超极化气体(3H和129Xe)和氙k边同步加速器x射线减影成像等新技术也在开发中,为研究人员提供了多种方法来探测气道、药物分布以及随后的摄取和生物分布。本文回顾了成像方面的进展,以呈现可用工具的当代观点。
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Imaging the airways in 2006.

Imaging has traditionally been separated into two distinct disciplines: functional imaging and structural imaging. Functional imaging encompasses applications such as nuclear medicine (single photon emission computed tomography [SPECT] and positron emission tomography [PET]), autoradiography, magnetic resonance spectroscopy (MRS) and magneto-encephalography (MEG), while structural, or anatomical, imaging includes planar radiography, x-ray computed tomography (CT), and magnetic resonance imaging (MRI). However, today, the distinctions between these are blurring due to advances in software fusion and the development of multi-modality (SPECT/CT, PET/CT) scanners. New techniques such as MRI using hyperpolarized gases (3H and 129Xe) and xenon K-edge synchrotron x-ray subtraction imaging are also being developed to provide the researcher with a variety of ways to probe the airways, and the distribution of pharmaceuticals and subsequent uptake and bio-distribution. This paper reviews advances in imaging to present a contemporary view of the tools available.

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