在幼儿中,面罩和气溶胶通过计量吸入器阀控制室输送:紧密密封使其不同。

H M Janssens, H A W Tiddens
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引用次数: 35

摘要

带阀保持室(VHC)上的面罩有助于幼儿从计量吸入器(MDI)吸入气溶胶。直到最近,口罩才被认为是有效输送气溶胶的重要组成部分。几项体外和体内研究表明,口罩的紧密密封对于最佳的气溶胶沉积到肺部至关重要。即使是很小的泄漏也会大大减少输送到肺部的剂量。然而,当孩子不合作时,很难获得紧密的密封。根据口罩的设计,更容易获得良好的密封。设计口罩时应考虑死区、形状和材料等因素。然而,当孩子在管理期间心烦意乱且不合作时,即使使用设计最好的口罩,气溶胶沉积也将是最小的。
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Facemasks and aerosol delivery by metered dose inhaler-valved holding chamber in young children: a tight seal makes the difference.

A facemask on a valved holding chamber (VHC) facilitates the inhalation of aerosols from metered dose inhalers (MDI) for young children. Only recently the facemask has been recognized as a vital part for efficient aerosol delivery. Several in vitro and in vivo studies show that a tight seal of the facemask is crucial for optimal aerosol deposition to the lungs. Even a small leak can reduce the dose delivered to the lungs considerably. However, a tight seal is difficult to obtain when a child is not cooperative. Depending on the design of the facemask, it is easier to obtain a good seal. Factors such as dead space, shape, and material should be considered when designing a facemask. However, when a child is upset and not cooperative during the administration, aerosol deposition will be minimal, even with the best-designed facemask.

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