模拟髋关节和膝关节置换手术的需求。第2部分。结合人口普查数据,在不确定范围内提供小范围的预测。

Andy Judge, Nicky J Welton, Jat Sandhu, Yoav Ben-Shlomo
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引用次数: 13

摘要

目的:建立对髋关节和膝关节置换术需求进行小范围评估的方法,为地方卫生服务规划提供信息。方法:采用多水平泊松回归模型,通过一项具有全国代表性的人口调查(英国老龄化纵向研究,n = 11,392名年龄>或=50岁的人),按年龄、性别、贫困、农村和种族混合来估计髋关节/膝关节置换术的需求率。然后将回归模型的需求估计与分层普查人口计数相结合,以产生小区域需求预测。预测中的不确定性是利用WinBUGS软件采用基于贝叶斯模拟的方法得到的。这使得参数估计中的相关性可以适当地纳入小区域预测的可信区间。结果:小范围估计需要髋关节/膝关节置换术已产生在英格兰的病房和地区。需求率根据一个地区的社会人口特征进行调整,并包括95%可信区间。髋关节/膝关节置换术的需求因地域而异,这取决于一个地区的社会人口特征。结论:首次对髋关节/膝关节置换手术的小范围需求进行了估计,并对不确定性进行了估计,为当地的卫生规划提供了信息。这里描述的方法方法可在其他国家和其他疾病指标中复制。需要进一步的研究,将小地区的需求估计与提供结合起来,以确定是否有公平获得保健的机会。
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Modeling the need for hip and knee replacement surgery. Part 2. Incorporating census data to provide small-area predictions for need with uncertainty bounds.

Objective: To develop methods to produce small-area estimates of need for hip and knee replacement surgery to inform local health service planning.

Methods: Multilevel Poisson regression modeling was used to estimate rates of need for hip/knee replacement by age, sex, deprivation, rurality, and ethnic mix using a nationally representative population-based survey (the English Longitudinal Study of Ageing, n = 11,392 people age > or =50 years). Estimates of need from the regression model were then combined with stratified census population counts to produce small-area predictions of need. Uncertainty in the predictions was obtained by taking a Bayesian simulation-based approach using WinBUGS software. This allows correlations in parameter estimates to be appropriately incorporated in the credible intervals for the small-area predictions.

Results: Small-area estimates of need for hip/knee replacement have been produced for wards and districts in England. Rates of need are adjusted for the sociodemographic characteristics of an area and include 95% credible intervals. Need for hip/knee replacement varies geographically, dependant on the sociodemographic characteristics of an area.

Conclusion: For the first time, small-area estimates of need for hip/knee replacement surgery have been produced together with estimates of uncertainty to inform local health planning. The methodologic approach described here could be reproduced in other countries and for other disease indicators. Further research is required to combine small-area estimates of need with provision to determine whether there is equitable access to care.

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Arthritis and rheumatism
Arthritis and rheumatism 医学-风湿病学
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