Zhi Ya Ma, Dosi Dosev, Mikaela Nichkova, Shirley J Gee, Bruce D Hammock, Ian M Kennedy
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Synthesis and bio-functionalization of multifunctional magnetic Fe(3)O(4)@Y(2)O(3):Eu nanocomposites.
A facile homogenous precipitation method has been developed for the synthesis of multifunctional, magnetic, luminescent nanocomposites with Fe(3)O(4) nanoparticles as the core and europium-doped yttrium oxide (Y(2)O(3):Eu) as the shell. The nanocomposites showed both super-paramagnetic behavior and unique europium fluorescence properties with high emission intensity. Their surface has been modified with a bifunctional ligand, p-aminobenzoic acid (PABA), and further biofunctionalized with biotin; the nanocomposites showed specific targeting for avidin-coupled polystyrene beads.
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