[5'-去甲马霉素N¹-氧化物类似物的合成及对牛痘病毒的抗病毒评价]。

Bioorganicheskaia khimiia Pub Date : 2010-11-01
E S Matiugina, K L Seley-Radtke, V L Andronova, G A Galegov, S N Kochetkov, A L Khandazhinskaia
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引用次数: 0

摘要

合成了5'-去甲马霉霉素N¹-氧化物类似物的N¹-苄基酯,并在牛痘病毒感染的细胞系统中作为s -腺苷- l-同型半胱氨酸水解酶的潜在抑制剂进行了测试。
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[Synthesis and antiviral evaluation against Vaccinia virus of new N¹-oxide analogues of 5'-noraristeromycin].

New N¹-benzyl esters of N¹-oxide analogues of 5'-noraristeromycin were synthesized and tested as potential inhibitors of S-adenosyl-L-homocysteine hydrolase in Vaccinia virus infected cell systems.

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