50-65岁丹麦人对带状疱疹的认识和对带状疱疹疫苗接种的态度。

Danish medical bulletin Pub Date : 2011-12-01
Gitte Lee Mortensen
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引用次数: 0

摘要

简介:带状疱疹(HZ或带状疱疹)及其并发症带状疱疹后神经痛(PHN)常见于50岁以上人群。一种降低HZ相关发病率和发病率的疫苗于2006年获得使用许可,并将于2013年在丹麦上市。本研究旨在探讨带状疱疹疾病认知与带状疱疹疫苗接种态度之间的关系。材料与方法:采用3次定性焦点小组访谈法对22名患者、家属和无HZ个人经历的个体进行访谈。采用半结构化访谈指南,包括在文献研究中确定的问题。使用医学人类学方法对数据进行了分析。结果:研究表明,尤其是HZ和PHN对患者的生活质量(QoL)有严重影响,并经常影响其亲属的日常生活。然而,没有HZ经历的人低估了其患病率和对生活质量的影响。这种误解往往导致延误治疗,并可能导致带状疱疹疫苗接种率低。结论:个体对带状疱疹疫苗接种的态度与对HZ的主观认知和对一般疫苗接种的看法密切相关。对目标人群的疫苗接种建议是必要的,但个人的选择取决于对疾病的了解、个人风险评估和全科医生的建议。资助:本研究由赛诺菲巴斯德MSD的研究资助。试验注册:不相关。
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Perceptions of herpes zoster and attitudes towards zoster vaccination among 50-65-year-old Danes.

Introduction: Herpes zoster (HZ or shingles) and its complication post-herpetic neuralgia (PHN) are common in persons above 50 years of age. A vaccine that decreases the incidence and morbidity associated with HZ was licensed for use in 2006 and will be marketed in Denmark as from 2013. This study aimed to explore the relations between illness perceptions of shingles and attitudes towards zoster vaccination.

Material and methods: Three qualitative focus group interviews were conducted with 22 patients, relatives and individuals with no personal experiences with HZ. Semi-structured interview guides were applied including questions identified in a literature study. The data were analysed using a medical anthropological approach.

Results: The study showed that HZ and PHN, in particular, have severe impacts on patients' quality of life (QoL) and often affect their relatives' daily lives as well. Nevertheless, people who have no experience with HZ underrate both its prevalence and its QoL impacts. Such misperceptions often result in delayed treatment and may lead to a low uptake of zoster vaccination.

Conclusion: Individual attitudes towards zoster vaccination are closely related to subjective perceptions of HZ and views on vaccination in general. Vaccination recommendations to target groups are necessary, but individual choice is determined by knowledge about the disease, personal risk assessment and the recommendations of the general practitioner.

Funding: The study was funded by a research grant from Sanofi Pasteur MSD.

Trial registration: not relevant.

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Danish medical bulletin
Danish medical bulletin 医学-医学:内科
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