[脾切除术后免疫功能低下患者急性肺囊虫感染期间心脏骤停]。

Anestezjologia intensywna terapia Pub Date : 2011-07-01
Krzsztof Tracz, Anna Kuczewska, Jacek Kulesza
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引用次数: 0

摘要

背景:耶氏肺囊虫(旧称卡氏肺囊虫)可引起免疫功能低下患者的严重肺炎,最常见于HIV感染者。病例报告:一名68岁的男子,8年前接受了创伤性脾切除术,因未知病原体引起的感染性休克而心脏骤停后入院。他已经用各种抗生素治疗了三个星期,但没有好转。复苏后第2天,发现lgM抗猪肺囊虫抗体浓度高,开始大剂量曲美托啶治疗并持续2周,进一步治疗并发呼吸机相关性肺炎(鲍曼不动杆菌);患者最终康复,无任何神经系统后遗症,并在ITU住院4周后转至低依赖区。结论:在脾切除术患者中,应怀疑乙氏肺囊虫感染是引起重症肺炎的原因。
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[Cardiac arrest during serve Pneumocystis jiroveci infection in an immune-compromised patient after splenectomy].

Background: Pneumocystis jiroveci (old name Pneumocystis carini) can cause severe pneumonia in immune-compromised patients, most commonly those who are HIV infected.

Case report: A 68-yr-old man, who eight years earlier had undergone trauma related splenectomy, was admitted to ITU after a cardiac arrest due to septic shock caused by unknown pathogen. He had been treated for three weeks with various antibiotics without improvement. On the second day after resuscitation, high concentration of lgM anti-Pneumocystis jivecii antibodies was found, and high-dose trimetoprim therapy was started and continued for two weeks, Further treatment was complicated by ventilator-associated pneumonia (Acinetobacter baumannii); the patient eventually recovered without any neurological sequelae, and was transferred to a low-dependency area after 4 weeks in ITU.

Conclusion: We conclude that Pneumocystis jiroveci infection should be suspected as a cause of severe pneumonia in splenectomised patients.

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