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Balancing sedation and ICU delirium management for better patient outcomes 平衡镇静和ICU谵妄管理以获得更好的患者结果
Pub Date : 2019-03-31 DOI: 10.5603/AIT.A2019.0007
K. Kotfis
A growing body of evidence suggests that patients treated in intensive care units (ICUs) are not only at risk of suffering from the severity of their underlying condition, but also from harmful and potentially iatrogenic problems, namely intensive care delirium and weakness [1]. This may be associated with an unfavourable long-term prognosis leading to physical, functional, cognitive and emotional breakdown after discharge from the ICU, as well as increased mortality and morbidity [2, 3]. The majority of critically ill patients are at risk of leaving the ICU incapable of independ-ent living and become a burden to their families and society. Therefore, the aim for an intensivist should be to provide critically ill patients with the maximum level of humane care and the minimum number of necessary interventions [4, 5]. In practice, this means adequate pain control, goal-directed sedation, assessment and adequate treatment of delirium, early mobility and the proper amount of overnight sleep [6]. In this issue of AIT, the findings of an observational cohort study, an im-portant evidence regarding assessment-guided sedation practices. In study, performed a group of 714 ventilated ICU patients, the investigators compared the outcome of two patient populations from before patients) and after patients) a the
越来越多的证据表明,在重症监护病房(icu)接受治疗的患者不仅面临着潜在疾病严重程度的风险,而且还面临着有害和潜在的医源性问题,即重症监护谵妄和虚弱bb0。这可能与不良的长期预后有关,导致从ICU出院后身体、功能、认知和情绪崩溃,并增加死亡率和发病率[2,3]。大多数危重患者有离开ICU后无法独立生活的危险,并成为家庭和社会的负担。因此,重症监护医师的目标应该是为危重患者提供最高水平的人道护理和最少数量的必要干预[4,5]。在实践中,这意味着适当的疼痛控制、目标导向的镇静、评估和充分治疗谵妄、早期活动和适当的夜间睡眠。在这一期的AIT中,一项观察性队列研究的结果,是评估指导镇静实践的重要证据。在这项研究中,研究人员对714名ICU患者进行了通气治疗,比较了两组患者(患者前和患者后)的结果
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引用次数: 1
[Patient satisfaction with anaesthesia and pre-anaesthetic information]. [患者对麻醉和麻醉前信息的满意度]。
Pub Date : 2011-10-01
Tomasz Gaszynski, Jakub Jakubiak, Katarzyna Woźniak, Tamara Trafidło, Paweł Ratajczyk, Wojciech Gaszyński

Background: Patient satisfaction with perioperative care plays an important role in the assessment of quality of care. Written evaluation forms are commonly used all over the world for this purpose. The aim of this study was to assess the quality of perioperative care, with special attention being directed to anaesthesia-associated side effects.

Methods: Forty-two adult patients, of both sexes, scheduled for abdominal surgery, were asked to complete a questionnaire consisting of 11 questions on anaesthesia, side effects and the general quality of perioperative care. The results were analysed using the X2 test, and p < 0.05 was considered significant. The Pearson correlation coefficient was used for comparison.

Results: There was a strong correlation between the quality of the pre-anaesthesia visit, including the information obtained on possible complications and alternative methods of anaesthesia, and the assessment of quality of the anaesthesia service. Post-anaesthesia care facilities were also found to be of major importance for patients.

Conclusions: Adequate, detailed and easily understandable information plays a crucial role in patients satisfaction with anaesthesia. Special attention should be paid to the most common side effects and complications. Residents should be trained in communication in the early stages of their training.

背景:患者对围手术期护理的满意度是评价护理质量的重要指标。书面评估表格在世界各地普遍用于此目的。本研究的目的是评估围手术期护理的质量,特别关注麻醉相关的副作用。方法:对42例拟行腹部手术的成年患者进行问卷调查,问卷内容包括麻醉、副作用及围手术期护理总体质量等11个问题。采用X2检验对结果进行分析,p < 0.05为显著性。采用Pearson相关系数进行比较。结果:麻醉前访视质量(包括获得的可能并发症和麻醉替代方法的信息)与麻醉服务质量评估之间存在很强的相关性。麻醉后护理设施也被发现对患者非常重要。结论:充分、详细、易懂的信息对麻醉患者的满意度起着至关重要的作用。应特别注意最常见的副作用和并发症。住院医师应在培训的早期阶段接受沟通方面的培训。
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引用次数: 0
[The clinical spectrum of connective tissue diseases - a single intensive care experience]. [结缔组织疾病的临床谱-一次重症监护经验]。
Pub Date : 2011-10-01
Danuta Gierek, Marcin Jezienicki, Tomasz Cyzowski, Henryka Chmurzewska, Eugeniusz Kucharz, Anna Kotulska, Józefa Dabek

Background: Systemic connective tissue diseases are relatively rare disorders of unknown origin, possibly related to autoimmunity. In the retrospective study, we analysed the records of nine patients suffering from connective tissue disorders who were treated during a two-year period in an intensive therapy unit.

Methods: Hospital medical records, observational charts and all other available medical documents were analysed.

Results: The clinical courses of 9 patients were studied. They included 4 with scleroderma, 3 with systemic lupus erythematosus, and 2 with inflammatory myopathy. They were admitted to the ITU because of sepsis and/or pneumonia, pulmonary haemorrhage, or cardiovascular failure. Three patients (2 with systemic sclerosis, 1 with systemic lupus erythematosus) died.

Conclusions: A multidisciplinary approach to treatment is a key factor in the successful management of patients with rare diseases, such as connective tissue pathologies. Frequent infections with respiratory and/or circulatory complications are the most common causes of severe morbidity in these patients.

背景:全身性结缔组织疾病是相对罕见的疾病,病因不明,可能与自身免疫有关。在回顾性研究中,我们分析了9名结缔组织疾病患者的记录,他们在强化治疗单位接受了两年的治疗。方法:对医院病历、观察图及其他所有可用的医学文献进行分析。结果:对9例患者的临床病程进行了分析。其中硬皮病4例,系统性红斑狼疮3例,炎性肌病2例。他们因败血症和/或肺炎、肺出血或心血管衰竭而被国际电联收治。3例患者(2例系统性硬化症,1例系统性红斑狼疮)死亡。结论:多学科联合治疗是成功治疗结缔组织病变等罕见疾病的关键因素。呼吸道和/或循环系统并发症的频繁感染是这些患者严重发病的最常见原因。
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引用次数: 0
[Suexametonium in paediatric anesthesia - an ambiguous issue]. [苏塞美溴铵在儿科麻醉中的应用——一个模棱两可的问题]。
Pub Date : 2011-10-01
Marcin Rawicz
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引用次数: 0
[Anaesthesiology in the Polish Armed Forces in the West during World War II]. [二战期间在西方的波兰武装部队的麻醉学]。
Pub Date : 2011-10-01
Aleksander Rutkiewicz, Izabela Duda, Ewa Musioł

Until the outbreak of WW II, anaesthesiology, as a separate specialty, did not exist in Poland. After the fall of Poland, a large section of the Polish Armed Forces was evacuated to France and after that, to the UK, where Polish military physicians had a unique opportunity to obtain training in modern anaesthesia. The first regular courses were established at the University of Edinburgh. After WW II, doctor Stanisław Pokrzywnicki, a pioneer of Polish anaesthesiology, who was trained by Sir Robert Macintosh, and doctor Bolesław Rutkowski, an anaesthesiologist in London, returned to Poland and started regular services. This led to the registering of anaesthesiology as a separate specialty in 1951. In the article, the wartime and post-war stories of the first Polish anaesthesiologists are presented.

直到第二次世界大战爆发,麻醉学作为一个独立的专业在波兰并不存在。波兰沦陷后,波兰武装部队的一大部分被疏散到法国,之后又被疏散到英国,在那里,波兰军医有一个独特的机会获得现代麻醉培训。最早的正规课程是在爱丁堡大学开设的。第二次世界大战后,波兰麻醉学的先驱、罗伯特·麦金托什爵士(Sir Robert Macintosh)训练过的医生Stanisław Pokrzywnicki和伦敦麻醉师Bolesław Rutkowski医生回到波兰,开始定期服务。这导致麻醉学在1951年注册为一个独立的专业。在文章中,第一批波兰麻醉师的战时和战后的故事被呈现。
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引用次数: 0
[Thromboelastography]. [Thromboelastography]。
Pub Date : 2011-10-01
Dominika Woźniak, Barbara Adamik

Coagulopathies of various origins have been mentioned among the leading causes of morbidity in hospitals all over the world. Time-consuming coagulation assays delay the diagnosis and response to a dynamic pathology. The need to analyse whole blood for the accurate identification of coagulopathies has led to a revival of interest in thromboelastography (TEG). This simple test can be performed at the bedside using non-anticoagulated blood, and enables complex assessment of extrinsic and intrinsic pathways of coagulation and fibrinolysis. TEG can be also used to predict postoperative bleeding and/or organ dysfunction. TEG has been widely used in research, but poor understanding of the technique has limited its clinical use. Controversies regarding the relationship between traditional tests and TEG have made the bedside use of TEG less popular than it should be. In the review, the authors discuss details of the process and practical aspects of its use in clinical settings.

各种来源的凝血病被认为是世界各地医院发病的主要原因之一。耗时的凝血检测延迟了动态病理的诊断和反应。需要分析全血凝血病的准确识别已经导致了对血栓弹性成像(TEG)的兴趣的复兴。这项简单的测试可以在床边使用非抗凝血进行,并且可以对凝血和纤溶的外在和内在途径进行复杂的评估。TEG也可用于预测术后出血和/或器官功能障碍。TEG已广泛应用于研究,但对该技术的不了解限制了其临床应用。关于传统测试和TEG之间关系的争议使得TEG的临床应用不那么受欢迎。在回顾中,作者讨论了其在临床应用的过程和实际方面的细节。
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引用次数: 0
Impact of the perioperative care model on mortality of patients treated in general surgery wards. 围手术期护理模式对普外科病房患者死亡率的影响。
Pub Date : 2011-10-01
Mariusz Piechota

Background: The risk of perioperative death in general surgery wards depends on many factors, including the underlying disease, type of surgical intervention and model of perioperative management. The aim of the study was to determine the reasons for major differences in mortality rates recorded in general surgery wards of the three university hospitals.

Methods: The retrospective study was carried out and involved the data of 32 231 surgical patients. In one of the hospitals, postoperative patients were treated in the recovery room supervised by anaesthetists; in the remaining two, perioperative care was delivered by surgical ward staff. A multiple regression model with random effects was used to adjust for differences in three death risk groups of patients according to underlying diseases: low, moderate and high.

Results: In the hospital with postoperative care administered by anaesthetic staff the mortality rate was 0.45 whereas in the two remaining ones with postoperative patients supervised by surgical staff - 1.86 and 2.52. In each group, increased mortality was observed among patients receiving therapy in general surgery wards after transfer from another hospital ward.

Conclusion: The major factor determining the mortality rates in general surgery wards is the model of perioperative management.

背景:普通外科病房围手术期死亡的风险取决于多种因素,包括基础疾病、手术干预类型和围手术期管理模式。该研究的目的是确定三所大学附属医院普通外科病房记录的死亡率存在重大差异的原因。方法:对32 231例手术患者进行回顾性研究。在其中一家医院,术后患者在恢复室接受治疗,由麻醉师监督;在其余两例中,围手术期护理由外科病房工作人员提供。采用随机效应的多元回归模型,对低、中、高三种基础疾病患者死亡风险组的差异进行校正。结果:术后有麻醉人员监护的医院死亡率为0.45,术后有外科人员监护的医院死亡率为1.86,术后有外科人员监护的医院死亡率为2.52。在每一组中,从其他医院病房转到普通外科病房接受治疗的患者死亡率均有所增加。结论:决定普通外科病房病死率的主要因素是围手术期管理模式。
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引用次数: 0
[Tricuspidal valve rupture after blunt chest trauma]. [钝性胸外伤后三尖瓣破裂]。
Pub Date : 2011-10-01
Wojciech Dąbrowski, Andrzej Nestorowicz, Jarosław Wośko, Przemysław Zadora, Adrzej Tomaszewski, Cezary Jurko

Background: Blunt chest trauma is frequently associated with cardiac contusion and structural damage, most cases only being recognized after death. We report a case of multiple organ trauma, where cardiac failure, caused by tricuspid valve rupture, was markedly delayed.

Case report: A 21 yr old man was admitted to hospital after a car accident. He was suffering from cerebral contusion and oedema, pulmonary contusion, and a left pneumothorax. He also had multiple fractures of the facial bones, orbit, L4 vertebra and left tibia. He was tracheotomised, and a subdural sensor was inserted for continuous monitoring of intracranial pressure. He was sedated and ventilated for two weeks. On the 12th day, his jaw was reconstructed, and immediately after surgery, mild signs of cardiac failure were observed, which were attributed to cardiac contusion. Two weeks after admission, the patient was weaned from the ventilator, and three days later, his facial bones were reconstructed. Four days later, the signs of cardiac failure reappeared. Transoesophageal echocardiography revealed rupture of a head of papillary muscle, with 4th degree tricuspid insufficiency and enlargement of the right ventricle. The ruptured muscle was reconstructed under extracorporeal circulation, and the patient made a satisfactory recovery.

Discussion: Acute tricuspid valve insufficiency, albeit rare, may occur in patients with blunt chest trauma. Sedation and lack of physical activity may delay the definite diagnosis, especially when only transthoracic echocardiography is used. Cardiac arrhythmias, diastolic murmur, or signs of congestive cardiac failure in a chest trauma patient may all suggest some structural damage; therefore, transoesophageal echocardiography should be performed as early as possible in such situations.

背景:钝性胸部外伤常伴有心脏挫伤和结构损伤,大多数病例在死亡后才被发现。我们报告一例多器官创伤,心衰,引起的三尖瓣破裂,明显延迟。病例报告:一名21岁男子因车祸入院。他患有脑挫伤、水肿、肺挫伤和左侧气胸。他还有多处面骨、眼眶、L4椎体和左胫骨骨折。患者气管切开,插入硬膜下传感器连续监测颅内压。他被打了两周的镇静剂和呼吸机。术后第12天进行下颌重建,术后立即出现轻度心力衰竭,原因为心源性挫伤。入院2周后,患者脱离呼吸机,3天后,重建面部骨骼。四天后,心脏衰竭的迹象再次出现。经食管超声心动图显示乳头肌头破裂,伴有4度三尖瓣功能不全和右心室增大。在体外循环下对断裂肌肉进行重建,患者恢复良好。讨论:急性三尖瓣功能不全,虽然罕见,但可能发生在钝性胸外伤患者。镇静和缺乏体力活动可能会延迟明确的诊断,特别是当仅使用经胸超声心动图时。胸部外伤患者的心律失常、舒张期杂音或充血性心力衰竭的迹象都可能提示一些结构性损伤;因此,在这种情况下应尽早进行经食管超声心动图检查。
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引用次数: 0
[Effect of red blood cell transfusions on the frequency of infections in the ITU]. [红细胞输注对ITU感染频率的影响]。
Pub Date : 2011-10-01
Jarosław Mamak, Lech Krawczyk

Background: It has been suggested that red blood cell transfusions may affect the outcome and frequency of infection in patients treated in ITU settings. We have therefore retrospectively analysed the records of one hundred and sixty-three patients treated in a large tertiary intensive care unit, in order to find any relationship between red blod cell transfusions and the frequency of nosocomial infections.

Methods: The patients were allocated to two groups: T - those who were transfused and N - those who were not. Among the transfused patients, two further subgroups were selected: those who were transfused within 48 h before any signs of infection were observed (n), and those in whom the transfusion was more than 48 h before infection was noted (t).

Results: There was a statistically significant difference between groups T and N (50.9% vs 38.1% infected patients), but not between subgroups t and n.

Conclusions: Nosocomial infections were more frequently observed in patients who required red blood cell transfusion. Red blood cell transfusion cannot be regarded a sole factor affecting nosocomial infection rates.

背景:有研究表明,红细胞输注可能会影响在国际电联环境中接受治疗的患者的结局和感染频率。因此,我们回顾性分析了163名在大型三级重症监护病房治疗的患者的记录,以发现红细胞输注与医院感染频率之间的关系。方法:将患者分为输血组T组和未输血组N组。在输血的患者中,进一步选择了两个亚组:在观察到感染迹象前48 h内输血的患者(n)和在感染前48 h输血的患者(t)。结果:t组与n组之间差异有统计学意义(50.9% vs 38.1%),而t组与n组之间差异无统计学意义。医院感染在需要输血的患者中更为常见。红细胞输注不能视为影响医院感染率的唯一因素。
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引用次数: 0
[Pain treatment in the emergency department: what do patients think?]. 急诊科的疼痛治疗:患者怎么看?
Pub Date : 2011-10-01
Sylweriusz Kosiński, Bogusława Siudut

Background: Pain on admission, especially after trauma, is the most common complaint (over 80%) of patients in the emergency department. During a four-week period, an anonymous, voluntary survey on the quality of pain management was conducted among adult patients reporting to the emergency department.

Methods: Five hundred questionnaires were distributed during admission, and 260 were returned. Patients were asked about localisation and severity of pain (NRS - Numerical Rating Scale), the quality and speed of assistance in the emergency department, and the effectiveness of analgesia.

Results: Ninety percent of patients reported pain of varying intensity. The median pain scores on admission were 5.2, 7.3 during management, and 3.8 on discharge. Over 90% of patients were questioned about pain, but only 20% received some medication. Nevertheless, 80% of those surveyed were satisfied, and there was no correlation between the severity of pain and administration of analgesics. Fifty percent of patients received analgesics for home use, and 66% were instructed about further treatment.

Conclusions: Despite the frequency and intensity of pain, analgesics were rarely offered in the emergency department. A surprisingly high level of satisfaction was reported, despite suboptimal pain management. This indicates either that non-pharmacologic methods of pain treatment play an important role, or that the severity of pain is overestimated by patients.

背景:入院时疼痛,尤其是创伤后疼痛,是急诊科患者最常见的主诉(超过80%)。在为期四周的时间里,对到急诊科就诊的成年患者进行了一项关于疼痛管理质量的匿名自愿调查。方法:入院时发放问卷500份,回收问卷260份。患者被问及疼痛的部位和严重程度(NRS -数值评定量表),急诊科援助的质量和速度,以及镇痛的有效性。结果:90%的患者报告有不同程度的疼痛。入院时疼痛评分中位数为5.2,治疗期间为7.3,出院时为3.8。超过90%的患者被问及疼痛,但只有20%的患者接受了一些药物治疗。然而,80%的被调查者感到满意,并且疼痛的严重程度和止痛药的使用之间没有相关性。50%的患者接受了家庭使用的镇痛药,66%的患者接受了进一步治疗的指导。结论:尽管疼痛的频率和强度,但在急诊科很少提供镇痛药。尽管疼痛管理不理想,但令人惊讶的是满意度很高。这表明疼痛治疗的非药物方法发挥了重要作用,或者疼痛的严重程度被患者高估了。
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引用次数: 0
期刊
Anestezjologia intensywna terapia
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