{"title":"β-葡聚糖的抗氧化活性。","authors":"Kyoko Kofuji, Ayumi Aoki, Kazufumi Tsubaki, Masanori Konishi, Takashi Isobe, Yoshifumi Murata","doi":"10.5402/2012/125864","DOIUrl":null,"url":null,"abstract":"<p><p>β-Glucans extracted from barley, which mainly contains β-(1,3-1,4)-D-glucan, are used extensively as supplements and food additives due to their wide biologic activities, including a reduction in blood lipid level. In this study, the antioxidant activity of β-glucan was examined to assess potential new benefits associated with β-glucan, because oxidative stress is considered one of the primary causal factors for various diseases and aging. β-Glucan extracted from barley was found to possess significant antioxidant activity. The amount of antioxidant activity was influenced by different physiologic properties (e.g., structure and molecular size) of β-glucan, which varied depending on the source and extraction method used. The antioxidant activity of β-glucan was significantly higher than that of various polymers that are used as food additives. These results indicate that β-glucan has promise as a polymeric excipient for supplement and food additive with antioxidant and other benefits, which may contribute to enhancing health and beauty.</p>","PeriodicalId":14802,"journal":{"name":"ISRN Pharmaceutics","volume":" ","pages":"125864"},"PeriodicalIF":0.0000,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/125864","citationCount":"122","resultStr":"{\"title\":\"Antioxidant Activity of β-Glucan.\",\"authors\":\"Kyoko Kofuji, Ayumi Aoki, Kazufumi Tsubaki, Masanori Konishi, Takashi Isobe, Yoshifumi Murata\",\"doi\":\"10.5402/2012/125864\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>β-Glucans extracted from barley, which mainly contains β-(1,3-1,4)-D-glucan, are used extensively as supplements and food additives due to their wide biologic activities, including a reduction in blood lipid level. In this study, the antioxidant activity of β-glucan was examined to assess potential new benefits associated with β-glucan, because oxidative stress is considered one of the primary causal factors for various diseases and aging. β-Glucan extracted from barley was found to possess significant antioxidant activity. The amount of antioxidant activity was influenced by different physiologic properties (e.g., structure and molecular size) of β-glucan, which varied depending on the source and extraction method used. The antioxidant activity of β-glucan was significantly higher than that of various polymers that are used as food additives. These results indicate that β-glucan has promise as a polymeric excipient for supplement and food additive with antioxidant and other benefits, which may contribute to enhancing health and beauty.</p>\",\"PeriodicalId\":14802,\"journal\":{\"name\":\"ISRN Pharmaceutics\",\"volume\":\" \",\"pages\":\"125864\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.5402/2012/125864\",\"citationCount\":\"122\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ISRN Pharmaceutics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5402/2012/125864\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2012/2/19 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ISRN Pharmaceutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5402/2012/125864","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2012/2/19 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 122
摘要
从大麦中提取的β-葡聚糖主要含有β-(1,3-1,4)- d -葡聚糖,由于其广泛的生物活性,包括降低血脂水平,被广泛用作补充剂和食品添加剂。在这项研究中,研究人员检测了β-葡聚糖的抗氧化活性,以评估β-葡聚糖相关的潜在新益处,因为氧化应激被认为是各种疾病和衰老的主要原因之一。从大麦中提取的β-葡聚糖具有显著的抗氧化活性。β-葡聚糖的不同生理特性(如结构和分子大小)会影响其抗氧化活性,而这些生理特性因来源和提取方法的不同而不同。β-葡聚糖的抗氧化活性明显高于各种用作食品添加剂的聚合物。这些结果表明,β-葡聚糖作为一种具有抗氧化等功效的聚合物赋形剂和食品添加剂,可能有助于增进健康和美容。
β-Glucans extracted from barley, which mainly contains β-(1,3-1,4)-D-glucan, are used extensively as supplements and food additives due to their wide biologic activities, including a reduction in blood lipid level. In this study, the antioxidant activity of β-glucan was examined to assess potential new benefits associated with β-glucan, because oxidative stress is considered one of the primary causal factors for various diseases and aging. β-Glucan extracted from barley was found to possess significant antioxidant activity. The amount of antioxidant activity was influenced by different physiologic properties (e.g., structure and molecular size) of β-glucan, which varied depending on the source and extraction method used. The antioxidant activity of β-glucan was significantly higher than that of various polymers that are used as food additives. These results indicate that β-glucan has promise as a polymeric excipient for supplement and food additive with antioxidant and other benefits, which may contribute to enhancing health and beauty.