重新审视发育迟缓

Yonata Levy
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引用次数: 6

摘要

这篇文章提出了当前的神经生物学概念,强调了实足年龄在决定最佳发育中的关键作用。讨论了敏感期、经验预期、基因表达和基因-年龄相互作用的作用。“分裂者”和“整合者”之间的争论是根据本期特刊的评论文章提出的。本研究的结论是,在很大比例的病例中,早期诊断是可能的,避免了全面的发育迟缓/全面发育迟缓,并为早期干预开辟了可能性。有人进一步认为,研究方法也可能受益于早期诊断。©2013 Wiley期刊公司开发与残疾,2011;17:180-184。
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Developmental Delay Revisited

This article presents current neurobiological concepts that highlight the critical role of chronological age in determining optimal development. The role of sensitive periods, experience expectancy, gene expression, and gene–age interactions is discussed. The debate between “splitters” and “lumpers” is presented in light of the review articles in this special issue. The conclusion from this study is that in a significant proportion of cases, earlier diagnoses are possible, avoiding the all-encompassing developmental delay/global developmental delay, and opening up possibilities of early interventions. It is further argued that research methodology might benefit from early diagnoses as well. © 2013 Wiley Periodicals, Inc. Dev Disabil Res Rev 2011;17:180–184.

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