欧洲动物肉毒杆菌中毒研讨会。

Hanna Skarin, Annica Tevell Åberg, Cédric Woudstra, Trine Hansen, Charlotta Löfström, Miriam Koene, Luca Bano, Mikael Hedeland, Fabrizio Anniballi, Dario De Medici, Eva Olsson Engvall
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引用次数: 23

摘要

2012年6月在瑞典乌普萨拉举行了一次关于动物肉毒杆菌中毒的讲习班。其目的是通过聚集欧洲动物肉毒杆菌中毒专家,探讨该疾病在欧洲的现状,并提高兽医和其他参与生物防备工作的人员对该疾病的认识。动物肉毒杆菌中毒未被充分报道和诊断,但越来越多的报道以及从本次研讨会收集的信息表明,这是欧洲一个新出现的问题。研讨会分为4个会议:欧洲的动物肉毒杆菌中毒、该疾病背后的细菌、检测和诊断以及欧洲的合作和监测。在讲习班之前进行了一次电子调查,以确定三个最需要的讨论点,它们是:预防、准备和疫情应对;检测和诊断;以及欧洲的合作和监督。从这些讨论中得出的主要结论是,迫切需要用体外试验取代肉毒杆菌毒素检测的小鼠生物测定法,并且需要建立一个欧洲网络作为参考实验室,该网络还可以组织欧洲肉毒杆菌抗毒素和疫苗的供应。讨论了这样一个网络的基础,并在这里提出了建议以及讨论的结果和讲习班本身的摘要。
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The workshop on animal botulism in Europe.

A workshop on animal botulism was held in Uppsala, Sweden, in June 2012. Its purpose was to explore the current status of the disease in Europe by gathering the European experts in animal botulism and to raise awareness of the disease among veterinarians and others involved in biopreparedness. Animal botulism is underreported and underdiagnosed, but an increasing number of reports, as well as the information gathered from this workshop, show that it is an emerging problem in Europe. The workshop was divided into 4 sessions: animal botulism in Europe, the bacteria behind the disease, detection and diagnostics, and European collaboration and surveillance. An electronic survey was conducted before the workshop to identify the 3 most needed discussion points, which were: prevention, preparedness and outbreak response; detection and diagnostics; and European collaboration and surveillance. The main conclusions drawn from these discussions were that there is an urgent need to replace the mouse bioassay for botulinum toxin detection with an in vitro test and that there is a need for a European network to function as a reference laboratory, which could also organize a European supply of botulinum antitoxin and vaccines. The foundation of such a network was discussed, and the proposals are presented here along with the outcome of discussions and a summary of the workshop itself.

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