取代羟胺的糖硅氧烷化衍生物。2取代羟基丙烷氨基葡萄糖的相转移合成及糖基转移反应研究[j]。

V O Kur'ianov, A A Lushchik, T A Chupakhina
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引用次数: 0

摘要

1-(2-乙酰氨基-3,4,6,- 3 - o-乙酰-2-脱氧- β -d -葡萄糖吡喃氧基)-苯并三唑在煮沸的二氯甲烷中反应,在路易斯酸作为启动子的存在下与伯、仲脂肪醇和环脂肪醇和二异丙烯半乳糖与烷基- o- 1,2-反式氨基葡萄糖生成。结果表明,取代羟胺的其他氨基葡萄糖不参与该反应。利用核磁共振光谱对氨基葡萄糖进行了结构鉴定,并与已知化合物进行了比较。
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[Glycosilated derivatives of substituted hydroxylamine. II. Phase transfer synthesis and investigation of glycosyl transfer reaction of glucosaminides of substituted hydroxylavine].

1-(2-Acetamido-3,4,6,-tri-O-acetyl-2-deoxy-beta-D-glucopyranosyloxy)-benzotriazole reacted in boiling dichloromethane, in the presence of Luis acids as a promotors with primary and secondary aliphatic and cycloaliphatic alcohols and diisopropilidene galactose with alkyl-O-1,2-trans-glucosaminides formation. It was shown that the other glucosaminides of substituted hydroxylamine are not participated in this reaction. Structures of glucosaminides were identify by 1H-NMR-spectroscopy and comparison with known compounds.

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