尼日利亚牙科保健服务中的抗生素处方。

C C Azodo, P I Ojehanon
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摘要

简介:在牙科保健服务中,不适当的抗生素处方可能导致抗生素耐药细菌的出现,这是一个全球关注的问题。本研究的目的是确定尼日利亚牙医的抗生素知识和处方模式。材料和方法:共向参加由尼日利亚南部和北部两个组织组织的继续教育课程的牙医分发了160份问卷。数据分析采用SPSS 17.0版本。结果:160份问卷中,共回收问卷146份,填写正确,总体回复率为91.3%。临床因素主要影响应答者对治疗性抗生素的选择。在这项研究中,受访者中最常开的抗生素是阿莫西林和甲硝唑的联合用药。在答复者中,136人(93.2%)认为抗生素耐药性是尼日利亚的一个主要问题,102人(69.9%)在牙科诊所中经历过抗生素耐药性。受访者中报告的主要预防性抗生素使用情况为糖尿病、HIV/AIDS、风湿热史、以心脏杂音和假髋关节为表现的其他心脏异常。对抗生素不良反应的了解最多的是与四环素有关的牙齿变色。结论:这项研究的数据显示,最常用的抗生素处方是阿莫西林和甲硝唑的组合。受访牙医在预防性抗生素处方、治疗性抗生素选择考虑、抗生素不良反应认知等方面存在差距。
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Antibiotics prescription in Nigerian dental healthcare services.

Introduction: Inappropriate antibiotics prescription in dental healthcare delivery that may result in the emergence of antibiotic-resistant bacteria, is a worldwide concern. The objective of the study was to determine the antibiotics knowledge and prescription patterns among dentists in Nigeria.

Materials and methods: A total of 160 questionnaires were distributed to dentists attending continuing education courses organized by two organizations in Southern and Northern parts of Nigeria. Data analysis was done using SPSS version 17.0.

Results: A total of 146 questionnaires were returned, properly filled, out of 160 questionnaires, giving an overall response rate 91.3%. The clinical factors predominantly influenced the choice of therapeutic antibiotics among the respondents. In this study, the most commonly prescribed antibiotics among the respondents was a combination of amoxicillin and metronidazole. Of the respondents, 136 (93.2%) of them considered antibiotic resistance as a major problem in Nigeria and 102 (69.9%) have experienced antibiotics resistance in dental practice. The major reported conditions for prophylactic antibiotics among the respondents were diabetic mellitus, HIV/AIDS, history of rheumatic fever, other heart anomalies presenting with heart murmur and presence of prosthetic hip. The knowledge of adverse effects of antibiotics was greatest for tooth discoloration which is related to tetracycline.

Conclusion: Data from this study revealed the most commonly prescribed antibiotics as a combination of amoxicillin and metronidazole. There existed gaps in prophylactic antibiotic prescription, consideration in the choice of therapeutic antibiotics and knowledge of adverse effects of antibiotics among the studied dentists.

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