枝源性癌鉴别诊断的临床争议。

IF 0.4 Q4 OTORHINOLARYNGOLOGY Case Reports in Otolaryngology Pub Date : 2022-09-16 eCollection Date: 2022-01-01 DOI:10.1155/2022/4582262
Alexander Karatzanis, Kleanthi Mylopotamitaki, Eleni Lagoudaki, Emmanuel Prokopakis, Sofia Agelaki
{"title":"枝源性癌鉴别诊断的临床争议。","authors":"Alexander Karatzanis,&nbsp;Kleanthi Mylopotamitaki,&nbsp;Eleni Lagoudaki,&nbsp;Emmanuel Prokopakis,&nbsp;Sofia Agelaki","doi":"10.1155/2022/4582262","DOIUrl":null,"url":null,"abstract":"<p><p>Clinical evaluation, differential diagnosis, and management of a neck mass constitute commonly encountered problems for the head and neck surgeon. An asymptomatic neck mass in adults may be the only clinical sign of head and neck cancer. A 50-year-old female patient presented with a painless, slowly enlarging, left lateral neck lump. Ultrasonography described a possible lymph node with cystic degeneration, and fine needle aspiration biopsy only detected atypical cells of squamous epithelium. An open biopsy under general anesthesia was performed. Histopathological findings suggested the diagnosis of lymph node infiltration by squamous cell carcinoma of an unknown primary site, but differential diagnosis also included branchiogenic carcinoma arising in a branchial cleft cyst. A diagnostic algorithm for metastatic squamous cell carcinoma of an unknown primary site was followed, including positron emission tomography with computed tomography. The patient underwent panendoscopy and bilateral tonsillectomy, and an ipsilateral p16 positive tonsillar squamous cell carcinoma was detected. Further appropriate management followed. The existence of true branchiogenic carcinoma is controversial. When such a diagnosis is contemplated, every effort should be made to detect a possible primary site. Branchiogenic carcinoma, if exists at all, remains a diagnosis of exclusion.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2022 ","pages":"4582262"},"PeriodicalIF":0.4000,"publicationDate":"2022-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529529/pdf/","citationCount":"1","resultStr":"{\"title\":\"Clinical Controversy Surrounding the Differential Diagnosis of Branchiogenic Carcinoma.\",\"authors\":\"Alexander Karatzanis,&nbsp;Kleanthi Mylopotamitaki,&nbsp;Eleni Lagoudaki,&nbsp;Emmanuel Prokopakis,&nbsp;Sofia Agelaki\",\"doi\":\"10.1155/2022/4582262\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Clinical evaluation, differential diagnosis, and management of a neck mass constitute commonly encountered problems for the head and neck surgeon. An asymptomatic neck mass in adults may be the only clinical sign of head and neck cancer. A 50-year-old female patient presented with a painless, slowly enlarging, left lateral neck lump. Ultrasonography described a possible lymph node with cystic degeneration, and fine needle aspiration biopsy only detected atypical cells of squamous epithelium. An open biopsy under general anesthesia was performed. Histopathological findings suggested the diagnosis of lymph node infiltration by squamous cell carcinoma of an unknown primary site, but differential diagnosis also included branchiogenic carcinoma arising in a branchial cleft cyst. A diagnostic algorithm for metastatic squamous cell carcinoma of an unknown primary site was followed, including positron emission tomography with computed tomography. The patient underwent panendoscopy and bilateral tonsillectomy, and an ipsilateral p16 positive tonsillar squamous cell carcinoma was detected. Further appropriate management followed. The existence of true branchiogenic carcinoma is controversial. When such a diagnosis is contemplated, every effort should be made to detect a possible primary site. Branchiogenic carcinoma, if exists at all, remains a diagnosis of exclusion.</p>\",\"PeriodicalId\":45872,\"journal\":{\"name\":\"Case Reports in Otolaryngology\",\"volume\":\"2022 \",\"pages\":\"4582262\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2022-09-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529529/pdf/\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Otolaryngology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/2022/4582262\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"OTORHINOLARYNGOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Otolaryngology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2022/4582262","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
引用次数: 1

摘要

临床评估、鉴别诊断和颈部肿块的处理是头颈部外科医生经常遇到的问题。成人无症状颈部肿块可能是头颈癌的唯一临床征象。一个50岁的女性病人表现为无痛,缓慢扩大,左侧颈部肿块。超声检查显示可能有淋巴结伴囊性变性,细针穿刺活检仅检出鳞状上皮的非典型细胞。全麻下行开放性活检。组织病理学结果提示原发部位未知的鳞状细胞癌淋巴结浸润,但鉴别诊断也包括鳃裂囊肿引起的鳃裂癌。一个诊断算法转移鳞状细胞癌的未知原发部位遵循,包括正电子发射断层扫描与计算机断层扫描。患者接受了全内窥镜检查和双侧扁桃体切除术,发现同侧p16阳性扁桃体鳞状细胞癌。随后进行了进一步的适当管理。真正的枝源性癌的存在是有争议的。当考虑这样的诊断时,应尽一切努力发现可能的原发部位。如果存在支原性癌,仍然是一种排除性诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Clinical Controversy Surrounding the Differential Diagnosis of Branchiogenic Carcinoma.

Clinical evaluation, differential diagnosis, and management of a neck mass constitute commonly encountered problems for the head and neck surgeon. An asymptomatic neck mass in adults may be the only clinical sign of head and neck cancer. A 50-year-old female patient presented with a painless, slowly enlarging, left lateral neck lump. Ultrasonography described a possible lymph node with cystic degeneration, and fine needle aspiration biopsy only detected atypical cells of squamous epithelium. An open biopsy under general anesthesia was performed. Histopathological findings suggested the diagnosis of lymph node infiltration by squamous cell carcinoma of an unknown primary site, but differential diagnosis also included branchiogenic carcinoma arising in a branchial cleft cyst. A diagnostic algorithm for metastatic squamous cell carcinoma of an unknown primary site was followed, including positron emission tomography with computed tomography. The patient underwent panendoscopy and bilateral tonsillectomy, and an ipsilateral p16 positive tonsillar squamous cell carcinoma was detected. Further appropriate management followed. The existence of true branchiogenic carcinoma is controversial. When such a diagnosis is contemplated, every effort should be made to detect a possible primary site. Branchiogenic carcinoma, if exists at all, remains a diagnosis of exclusion.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Case Reports in Otolaryngology
Case Reports in Otolaryngology OTORHINOLARYNGOLOGY-
自引率
0.00%
发文量
20
审稿时长
13 weeks
期刊最新文献
Schwannoma at an Unusual Site: Case Report and Surgical Technique Discussion for Nasal Dorsum. Lemierre Syndrome with Extensive Thrombosis: A Unique Case Report and Literature Review. New Instruments for the Management of Cochlear Implantation in an Individual with a Fracture of the Temporal Bone and Cochlear Ossification. Ectopic Salivary Gland Found in the Vocal Cord: A Rare Case. Pleomorphic Adenoma of the Palate: Diagnostic and Surgical Strategy.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1