剪切波弹性成像诊断慢性自身免疫性甲状腺炎的应用。

IF 1.7 Q4 ENDOCRINOLOGY & METABOLISM Journal of Thyroid Research Pub Date : 2015-01-01 Epub Date: 2015-07-16 DOI:10.1155/2015/164548
Takahiro Fukuhara, Eriko Matsuda, Shoichiro Izawa, Kazunori Fujiwara, Hiroya Kitano
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引用次数: 41

摘要

本研究的目的是评估使用声辐射力脉冲(ARFI)诊断慢性自身免疫性甲状腺炎(CAT)的剪切波弹性成像(SWE)的效用,并验证纤维化甲状腺组织对剪切波速度(SWV)的影响。229例正常甲状腺叶(对照)253例,CAT叶150例。CAT组的SWV(2.47±0.57 m/s)显著高于对照组(1.59±0.41 m/s) (P < 0.001)。CAT受试者工作特征(ROC)曲线下面积为0.899,SWV截止值为1.96 m/s。敏感性、特异性和诊断准确率分别为87.4%、78.7%和85.1%。抗甲状腺过氧化物酶抗体水平和甲状腺峡部厚度与CAT的组织僵硬度相关。然而,抗甲状腺球蛋白抗体水平与组织硬度之间没有相关性。定量SWE对CAT的诊断是有用的,并且有可能用于评估CAT患者的纤维化程度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Utility of Shear Wave Elastography for Diagnosing Chronic Autoimmune Thyroiditis.

The aims of this study were to evaluate the utility of shear wave elastography (SWE) using acoustic radiation force impulse (ARFI) for diagnosing chronic autoimmune thyroiditis (CAT) and to verify the effect of fibrotic thyroid tissue on shear wave velocity (SWV). The subjects were 229 patients with 253 normal thyroid lobes (controls) and 150 CAT lobes. The SWV for CAT (2.47 ± 0.57 m/s) was significantly higher than that for controls (1.59 ± 0.41 m/s) (P < 0.001). The area under the receiver operating characteristics (ROC) curve for CAT was 0.899, and the SWV cut-off value was 1.96 m/s. The sensitivity, specificity, and diagnostic accuracy were 87.4%, 78.7%, and 85.1%, respectively. Levels of anti-thyroperoxidase antibodies and thyroid isthmus thickness were correlated with tissue stiffness in CAT. However, there was no correlation between levels of anti-thyroglobulin antibodies and tissue stiffness. Quantitative SWE is useful for diagnosing CAT, and it is possible that SWE can be used to evaluate the degree of fibrosis in patients with CAT.

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来源期刊
Journal of Thyroid Research
Journal of Thyroid Research ENDOCRINOLOGY & METABOLISM-
CiteScore
4.40
自引率
0.00%
发文量
10
审稿时长
17 weeks
期刊最新文献
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