增加已知pictet - spenglerase的多样性。

Martin E Tanner
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引用次数: 4

摘要

pictet - spenglerase是生物碱合成过程中芳香族乙胺与醛之间的缩合/环化反应的关键催化剂。在本期的《化学与生物学》杂志上,Mori等人(2015)报道了一种新型参与β-碳碱生物碱生物合成的Pictet-Spenglerase的结构阐明。
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Increasing the Diversity of Known Pictet-Spenglerases.

Pictet-Spenglerases catalyze key condensation/cyclization reactions between aromatic ethylamines and aldehydes in the biosynthesis of alkaloids. In this issue of Chemistry & Biology, Mori et al. (2015) report the structural elucidation of a novel type of Pictet-Spenglerase involved in the biosynthesis of the β-carboline alkaloids.

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来源期刊
Chemistry & biology
Chemistry & biology 生物-生化与分子生物学
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4-8 weeks
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