外伤性肝损伤手术与非手术治疗的比较。

Ki Bum Park, Dong Do You, Tae Ho Hong, Jung Min Heo, Yong Sung Won
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引用次数: 8

摘要

背景/目的:本研究的目的是比较肝损伤患者的手术与非手术治疗,并确定临床特征的差异。方法:2000年4月至2012年7月,首尔圣玛丽医院和圣文森特医院共收治191例肝损伤患者。其中,148例患者纳入本研究。所有患者均采用计算机断层扫描(CT)进行诊断。肝损伤按照美国创伤外科协会肝损伤评分标准进行分级。患者分为两组:接受手术治疗和非手术治疗(NOM)。比较两组患者的临床特征、肝损伤程度、血流动力学稳定性、实验室结果和死亡率。结果:148例患者中,108例(72.9%)患者接受了NOM治疗,40例(27.1%)患者接受了手术。根据修订创伤损伤量表、损伤严重程度评分和格拉斯哥昏迷量表,接受NOM治疗的患者严重损伤明显减少。手术组肝损伤程度、CT造影剂外渗及腹腔积血数量均高于手术组。两组患者入院时和入院后4小时心率、呼吸频率、收缩压、平均血红蛋白水平均有显著差异。手术组的死亡率明显高于NOM组。结论:我们的研究结果提示,在决定肝损伤的治疗时应考虑血流动力学稳定性和以下因素:肝损伤等级、出血量和损伤量表评分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Comparison between operative versus non-operative management of traumatic liver injury.

Backgrounds/aims: The aim of this study was to compare operative versus non-operative management of patients with liver injury and to ascertain the differences of the clinical features.

Methods: From April 2000 to July 2012, 191 patients were admitted to Seoul St. Mary's Hospital and St. Vincent's Hospital for liver injuries. Of these, 148 patients were included in this study. All patients were diagnosed using computed tomography (CT). The liver injury was graded in accordance with the American Association for the Surgery of Trauma liver injury scoring scale. Patients were divided into two groups: those who underwent surgery and those treated with non-operative management (NOM). There was a comparison between these two groups concerning the clinical characteristics, grade of liver injury, hemodynamic stability, laboratory findings, and mortality.

Results: According to the 148 patient records evaluated, 108 (72.9%) patients were treated with NOM, and 40 (27.1%) underwent surgery. Patients treated with NOM had significantly fewer severe injuries as rated using the Revised Traumatic Injury Scale, Injury Severity Score, and Glasgow Coma Scale. Grade of liver injury and number of patients with extravasation of contrast dye on CT and hemoperitoneum were higher in the operative group than in the NOM group. There were significant differences between the two groups for: heart rate, respiratory rate, systolic blood pressure, and mean hemoglobin levels at admission and after 4 hours. The operative group experienced a significantly higher mortality than the NOM group.

Conclusions: The results of our study suggest that hemodynamic stability and the following should be considered for deciding the treatment for liver injuries: grade of liver injury, amount of blood loss, and injury scales scores.

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