胆管远端转移性粘液腺癌,来自横断结肠癌,表现为梗阻性黄疸。

Doo-Ho Lee, Young Joon Ahn, Rumi Shin, Hae Won Lee
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引用次数: 7

摘要

患者为70岁男性,主诉为梗阻性黄疸和体重减轻。腹部影像学检查显示胆总管远端有2.5 cm大小的肿块,提示胆管癌。横结肠壁增厚偏心性增强,提示合并结肠癌。结肠镜检查发现横结肠内有一环绕管腔的溃疡流出性肿块,病理证实为腺癌。胆管病理也为腺癌。在诊断为双原发癌的情况下,行保留幽门的胰十二指肠切除术和扩大的右半结肠切除术。术后组织病理学检查显示为横断面结肠癌中分化粘液腺癌和胆总管远端粘液腺癌。免疫组化染色显示胆管癌已从结肠癌转移。病人手术后恢复得很顺利,将接受三个月的化疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Metastatic mucinous adenocarcinoma of the distal common bile duct, from transverse colon cancer presenting as obstructive jaundice.

The patient was a 70-year-old male whose chief complaints were obstructive jaundice and weight loss. Abdominal imaging studies showed a 2.5 cm sized mass at the distal common bile duct, which was suggestive of bile duct cancer. Eccentric enhancing wall thickening in the transverse colon was also shown, suggesting concomitant colon cancer. A colonoscopy revealed a lumen-encircling ulcerofungating mass in the transverse colon, that was pathologically proven to be adenocarcinoma. The bile duct pathology was also adenocarcinoma. Pylorus-preserving pancreaticoduodenectomy and extended right hemicolectomy were performed under the diagnosis of double primary cancers. Postoperative histopathologic examination revealed moderately differentiated mucinous adenocarcinoma of transverse colon cancer, and mucinous adenocarcinoma of the distal common bile duct. Immunohistochemical staining studies showed that the bile duct cancer had metastasized from the colon cancer. The patient recovered uneventfully from surgery and will be undergoing chemotherapy for three months.

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