活体肝供者介入治疗缺血性胆道狭窄2例远期疗效分析

Dong-Hwan Jung, Shin Hwang, Tae-Yong Ha, Gi-Won Song, Ki-Hun Kim, Chul-Soo Ahn, Deok-Bog Moon, Gil-Chun Park, Bo-Hyun Jung, Sung-Hwa Kwang, Sung-Gyu Lee
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引用次数: 1

摘要

正常近端胆管壁偶见薄,靠近右肝动脉。因此,在半肝移植时,分离肝动脉会导致残余近端胆管壁过度弱化。这种类型的损伤可引起供体胆总管缺血性狭窄。本研究旨在回顾主要采用内镜和放射介入治疗的缺血性供体胆管损伤的临床序列。回顾性分析了两例缺血性胆管损伤的活体供者的医疗记录。他们被跟踪调查了10多年。右肝和左肝移植来自这两个供体。胆管解剖显示一侧为正常分叉,另一侧为异常分支。肝捐献后2周和1周分别检测到胆管狭窄。他们接受了内镜下球囊扩张和临时支架(内镜下逆行胆道引流管)置入。在保存试管2个月后,成功地将试管从一个供体中取出。然而,内窥镜治疗不成功,因此对其他供体进行额外的放射干预是必要的。随访超过10年,到目前为止,他们都很好,没有再发生胆道狭窄。根据我们有限的经验,介入治疗和随后的长期随访似乎是肝脏活体供者发生缺血性胆道狭窄的必要和选择的治疗方法。
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Long-term outcome of ischemic type biliary stricture after interventional treatment in liver living donors: a report of two cases.

The wall of normal proximal bile duct is occasionally thin with close approximation to the right hepatic artery. Thus, isolation of this hepatic artery can result in excessive weakening of the remnant proximal bile duct wall during hemiliver graft harvest. This type of injury can induce ischemic stricture of the donor common bile duct. This study aimed to review the clinical sequences of such ischemic type donor bile duct injuries primarily managed with endoscopic and radiological interventional treatments. A retrospective review of medical records was performed for two living donors who suffered from ischemic type donor bile duct injury. They were followed up for more than 10 years. The right and left liver grafts were harvested from these two donors. Bile duct anatomy was normal bifurcation in one and anomalous branching in the other. Bile duct stenosis was detected in them at 2 weeks and 1 week after liver donation. They underwent endoscopic balloon dilatation and temporary stent (endoscopic retrograde biliary drainage tube) insertion. After keeping the tube for 2 months, the tube was successfully removed in one donor. However, endoscopic treatment was not successful, thus additional radiological intervention was necessary in the other donor. On follow-up over 10 years, they are doing well so far with no recurrence of biliary stricture. Based on our limited experience, interventional treatment with subsequent long-term follow-up appears to be an essential and choice treatment for ischemic type biliary stricture occurring in liver living donors.

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