抗vegf注射与地理萎缩进展的关系。

Ophthalmology and eye diseases Pub Date : 2016-08-07 eCollection Date: 2016-01-01 DOI:10.4137/OED.S38863

Ryan Enslow, Sai Bhuvanagiri, Sravanthi Vegunta, Benjamin Cutler, Michael Neff, Brian Stagg

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引用次数: 26

摘要

年龄相关性黄斑变性(AMD)是发达国家60岁以上人群失明的主要原因之一。晚期AMD的一种形式是湿性AMD。湿性AMD是由异常新生血管形成引起的渗漏和出血的结果。湿性AMD的主要治疗方法是玻璃体内注射抗vegf。晚期AMD的第二种形式是地理萎缩(GA)。GA是指视网膜色素上皮大面积丢失。在文献中，有人担心注射抗vegf治疗湿性AMD可能与GA的进展有关。这篇综述讨论了抗vegf注射与GA进展相关的证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Association of Anti-VEGF Injections with Progression of Geographic Atrophy.

Age-related macular degeneration (AMD) is one of the leading causes of blindness in developed countries in people over the age of 60 years. One of the forms of advanced AMD is wet AMD. Wet AMD is a result of leakage and bleeding from abnormal neovascularization. The principal treatment for wet AMD is intravitreal anti-VEGF injections. A second form of advanced AMD is geographic atrophy (GA). GA refers to large areas of retinal pigment epithelium loss. In the literature, there is some concern that anti-VEGF injections administered to treat wet AMD may be associated with progression of GA. This review discusses evidence suggesting the association of anti-VEGF injections with progression of GA.

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